Articles | Volume 6, issue 7
https://doi.org/10.5194/jbji-6-283-2021
https://doi.org/10.5194/jbji-6-283-2021
Original full-length article
 | 
20 Jul 2021
Original full-length article |  | 20 Jul 2021

Ceramic composite with gentamicin decreases persistent infection and increases bone formation in a rat model of debrided osteomyelitis

Aleksey Dvorzhinskiy, Giorgio Perino, Robert Chojnowski, Marjolein C. H. van der Meulen, Mathias P. G. Bostrom, and Xu Yang

Viewed

Total article views: 1,536 (including HTML, PDF, and XML)
HTML PDF XML Total BibTeX EndNote
1,145 319 72 1,536 55 65
  • HTML: 1,145
  • PDF: 319
  • XML: 72
  • Total: 1,536
  • BibTeX: 55
  • EndNote: 65
Views and downloads (calculated since 20 Jul 2021)
Cumulative views and downloads (calculated since 20 Jul 2021)

Viewed (geographical distribution)

Total article views: 1,459 (including HTML, PDF, and XML) Thereof 1,459 with geography defined and 0 with unknown origin.
Country # Views %
  • 1
1
 
 
 
 

Cited

Latest update: 10 Jul 2025
Download
Short summary
Osteomyelitis is an infection of bone and is often treated with surgical debridement. This results in a bone defect which requires the use of a void filler. This study evaluated the use of a gentamicin-impregnated ceramic void filler (CERAMENT G) and compared it to the same void filler without antibiotic (CERAMENT) and no void filler in a rat model of osteomyelitis. CERAMENT G was found to decrease the rate of persistent infection and grow more new bone than CERAMENT or an empty defect.
Share