Recent  

Patients undergoing multiple hip and knee revision arthroplasty procedures for periprosthetic joint infection can have a changing microbiological picture, which can impact their management and outcomes. We aimed to investigate this using data from two large-volume orthopaedic centres. A total of 106 patients were identified; after six revision procedures, 90 % of patients had different organisms cultured compared with the initial revision and 53 % of the organisms were multidrug resistant.

We compared prosthetic joint infection (PJI) and acute kidney injury (AKI) rates among cohorts before and after changing our hospital's antimicrobial prophylaxis from cefuroxime to teicoplanin plus gentamicin for primary total joint arthroplasty. Switching to teicoplanin and gentamicin was associated with a significant risk reduction for PJI of 75.2 %. Significantly higher AKI rates were seen in patients receiving teicoplanin plus gentamicin; however, these were mild (KDIGO stage 1).

A total of 41 patients who underwent surgical treatment for septic arthritis (SA) of the native hip were studied. We show that patients with SA of the native hip can be divided in three distinct clinical subgroups based on route of infection. Route of infection is directly related to the chance of femoral head preservation and should, therefore, be the basis for decision-making. Only patients with blood-borne infections in an undamaged hip had a reasonable chance of femoral head preservation.

Tuberculosis (TB) primarily involves the lungs, but it may spread to other sites including joints. TB arthritis, is relatively rare, but it can result in severe damage to the joint and, ultimately, significant functional impairment. This article reviews the current literature on the topic and identifies key areas where further scientific research is needed to improve the diagnosis and management of the disease.