Articles | Volume 6, issue 7
https://doi.org/10.5194/jbji-6-257-2021
https://doi.org/10.5194/jbji-6-257-2021
Review
 | 
08 Jul 2021
Review |  | 08 Jul 2021

Systematic review of risk prediction studies in bone and joint infection: are modifiable prognostic factors useful in predicting recurrence?

Maria Dudareva, Andrew Hotchen, Martin A. McNally, Jamie Hartmann-Boyce, Matthew Scarborough, and Gary Collins

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Subject: Risk factors for bone and joint infections | Topic: All topics
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Cited articles

Ahmad, S. S., Orlik, L., Ahmad, S. J. S., Albers, C. E., Siebenrock, K. A., and Klenke, F. M.: Obesity and smoking predict the results of two-stage exchange in septic revision hip arthroplasty: a cohort study, Orthop. Traumatol., 105, 467–471, https://doi.org/10.1016/j.otsr.2019.01.006, 2019. 
Anderson, L. A., Culp, B. M., Della Valle, C. J., Gililland, J. M., Meneghini, R. M., Browne, J. A., and Springer, B. D.: High failure rates of concomitant periprosthetic joint infection and extensor mechanism disruption, J. Arthroplasty, 33, 1879–1883, https://doi.org/10.1016/j.arth.2018.01.022, 2018. 
Barr, T., Girke, T., Sureshchandra, S., Nguyen, C., Grant, K., and Messaoudi, I.: Alcohol consumption modulates host defence in rhesus macaques by altering gene expression in circulating leukocytes, J. Immunol., 196, 185–195, https://doi.org/10.4049/jimmunol.1501527, 2016. 
Barshes, N. R., Mindru, C., Ashong, C., Rodriguez-Barradas, M., and Trautner, B. W.: Treatment failure and leg amputation among patients with foot osteomyelitis, Int. J. Lower Extr. Wound., 15, 303–312, https://doi.org/10.1177/1534734616661058, 2016. 
Barton, C. B., Wang, D. L., An, Q., Brown, T. S., Callaghan, J. J., and Otero, J. E.: Two-stage exchange arthroplasty for periprosthetic joint infection following total hip or knee arthroplasty is associated with high attrition rate and mortality, J Arthroplasty, 35, 1384–1389, https://doi.org/10.1016/j.arth.2019.12.005, 2019. 
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Short summary
Clinical prognostic models are tools that predict treatment outcomes for individual patients. For adults with bone and joint infection treated with surgery and implant removal, this review found no existing unbiased clinical prediction models that took modifiable health factors into account to estimate prognosis. Developing a clinical prognostic model may help treatment decisions and future targeted research in orthopaedic infection.