Articles | Volume 7, issue 6
Original full-length article
14 Nov 2022
Original full-length article |  | 14 Nov 2022

Implant surface modifications as a prevention method for periprosthetic joint infection caused by Staphylococcus aureus: a systematic review and meta-analysis

Krisna Yuarno Phatama, Respati Suryanto Dradjat, Edi Mustamsir, Dwi Yuni Nurhidayati, Dewi Santosaningsih, Dwikora Novembri Utomo, and Mohamad Hidayat

Related subject area

Subject: Prosthesis-related infections | Topic: Prevention and control
The scientific publication score – a new tool for summarizing evidence and data quality criteria of biomedical publications
Dieter Bettin, Thomas Maurer, Ferdinand Schlatt, and Simon Bettin
J. Bone Joint Infect., 7, 269–278,,, 2022
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Unexpected positive intraoperative cultures (UPIC) at index osseointegration do not lead to increased postoperative infectious events
Jason S. Hoellwarth, Taylor J. Reif, Michael W. Henry, Andy O. Miller, Austin C. Kaidi, and S. Robert Rozbruch
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Cited articles

Aggarwal, V. K., Bakhshi, H., Ecker, N. U., Parvizi, J., Gehrke, T., and Kendoff, D.: Organism profile in periprosthetic joint infection: pathogens differ at two arthroplasty infection referral centers in Europe and in the United States, J. Knee Surg., 27, 399–406,, 2014. 
Anagnostakos, K. and Sahan, I.: Are cement spacers and beads loaded with the correct antibiotic(s) at the site of periprosthetic hip and knee joint infections?, Antibiotics, 10, 143,, 2021. 
Arciola, C. R., Campoccia, D., and Montanaro, L.: Implant infections: Adhesion, biofilm formation and immune evasion, Nat. Rev. Microbiol., 16, 397–409,, 2018. 
Beam, E. and Osmon, D.: Prosthetic Joint Infection Update, Infect. Dis. Clin. North Am., 32, 843–859,, 2018. 
Beyer, F., Lützner, C., Kirschner, S., and Lützner, J.: Midterm results after coated and uncoated TKA: A randomized controlled study, Orthopedics, 39, S13–S17,, 2016. 
Short summary
Every year the incidence of prosthetic joint infection (PJI) continues to increase. Therefore, it required a way to reduce complications, one of them coating methods. However, the best preventive strategy is still debatable. Through various review processes, it was finally discovered that coating methods using antibiotics were an effective method to prevent the occurrence of PJI, while coating with non-antibiotic materials such as silver and iodine is significant in preventing incidence of PJI.