Articles | Volume 7, issue 1
https://doi.org/10.5194/jbji-7-1-2022
https://doi.org/10.5194/jbji-7-1-2022
Original full-length article
 | 
06 Jan 2022
Original full-length article |  | 06 Jan 2022

Nuclear imaging does not have clear added value in patients with low a priori chance of periprosthetic joint infection. A retrospective single-center experience

Karsten D. Ottink, Stefan J. Gelderman, Marjan Wouthuyzen-Bakker, Joris J. W. Ploegmakers, Andor W. J. M. Glaudemans, and Paul C. Jutte

Related authors

Predicting periprosthetic joint infection: external validation of preoperative prediction models
Seung-Jae Yoon, Paul C. Jutte, Alex Soriano, Ricardo Sousa, Wierd P. Zijlstra, and Marjan Wouthuyzen-Bakker
J. Bone Joint Infect., 9, 231–239, https://doi.org/10.5194/jbji-9-231-2024,https://doi.org/10.5194/jbji-9-231-2024, 2024
Short summary
Potential value of a rapid syndromic multiplex PCR for the diagnosis of native and prosthetic joint infections: a real-world evidence study
Stéphanie Pascual, Brooklyn Noble, Nusreen Ahmad-Saeed, Catherine Aldridge, Simone Ambretti, Sharon Amit, Rachel Annett, Shaan Ashk O'Shea, Anna Maria Barbui, Gavin Barlow, Lucinda Barrett, Mario Berth, Alessandro Bondi, Nicola Boran, Sara E. Boyd, Catarina Chaves, Martin Clauss, Peter Davies, Ileana T. Dianzo-Delgado, Jaime Esteban, Stefan Fuchs, Lennart Friis-Hansen, Daniel Goldenberger, Andrej Kraševac Glaser, Juha O. Groonroos, Ines Hoffmann, Tomer Hoffmann, Harriet Hughes, Marina Ivanova, Peter Jezek, Gwennan Jones, Zeynep Ceren Karahan, Cornelia Lass-Flörl, Frédéric Laurent, Laura Leach, Matilde Lee Horsbøll Pedersen, Caroline Loiez, Maureen Lynch, Robert J. Maloney, Martin Marsh, Olivia Milburn, Shanine Mitchell, Luke S. P. Moore, Lynn Moffat, Marianna Murdjeva, Michael E. Murphy, Deepa Nayar, Giacomo Nigrisoli, Fionnuala O'Sullivan, Büşra Öz, Teresa Peach, Christina Petridou, Mojgan Prinz, Mitja Rak, Niamh Reidy, Gian Maria Rossolini, Anne-Laure Roux, Patricia Ruiz-Garbajosa, Kordo Saeed, Llanos Salar-Vidal, Carlos Salas Venero, Mathyruban Selvaratnam, Eric Senneville, Peter Starzengruber, Ben Talbot, Vanessa Taylor, Rihard Trebše, Deborah Wearmouth, Birgit Willinger, Marjan Wouthuyzen-Bakker, Brianne Couturier, and Florence Allantaz
J. Bone Joint Infect., 9, 87–97, https://doi.org/10.5194/jbji-9-87-2024,https://doi.org/10.5194/jbji-9-87-2024, 2024
Short summary
Wound drainage after arthroplasty and prediction of acute prosthetic joint infection: prospective data from a multicentre cohort study using a telemonitoring app
Henk Scheper, Rachid Mahdad, Brenda Elzer, Claudia Löwik, Wierd Zijlstra, Taco Gosens, Joris C. T. van der Lugt, Robert J. P. van der Wal, Rudolf W. Poolman, Matthijs P. Somford, Paul C. Jutte, Pieter K. Bos, Richard E. Zwaan, Rob G. H. H. Nelissen, Leo G. Visser, Mark G. J. de Boer, and the wound care app study group
J. Bone Joint Infect., 8, 59–70, https://doi.org/10.5194/jbji-8-59-2023,https://doi.org/10.5194/jbji-8-59-2023, 2023
Short summary
First evaluation of a commercial multiplex PCR panel for rapid detection of pathogens associated with acute joint infections
Jorrit Willem Adriaan Schoenmakers, Rosanne de Boer, Lilli Gard, Greetje Anna Kampinga, Marleen van Oosten, Jan Maarten van Dijl, Paulus Christiaan Jutte, and Marjan Wouthuyzen-Bakker
J. Bone Joint Infect., 8, 45–50, https://doi.org/10.5194/jbji-8-45-2023,https://doi.org/10.5194/jbji-8-45-2023, 2023
Short summary
Black pus from a worn-out elbow arthroplasty
Marjan Wouthuyzen-Bakker and Alexander L. Boerboom
J. Bone Joint Infect., 7, 33–34, https://doi.org/10.5194/jbji-7-33-2022,https://doi.org/10.5194/jbji-7-33-2022, 2022
Short summary

Related subject area

Subject: Prosthesis-related infections | Topic: Other
Changing the definition of treatment success alters treatment outcomes in periprosthetic joint infection: a systematic review and meta-analysis
Eytan M. Debbi, Tyler Khilnani, Ioannis Gkiatas, Yu-Fen Chiu, Andy O. Miller, Michael W. Henry, and Alberto V. Carli
J. Bone Joint Infect., 9, 127–136, https://doi.org/10.5194/jbji-9-127-2024,https://doi.org/10.5194/jbji-9-127-2024, 2024
Short summary
Diagnostic cutoff values of synovial fluid biomarkers for acute postoperative prosthetic joint infection: a systematic review and meta-analysis
Marta Sabater-Martos, Marc Ferrer, Laura Morata, Alex Soriano, and Juan Carlos Martínez-Pastor
J. Bone Joint Infect., 9, 17–26, https://doi.org/10.5194/jbji-9-17-2024,https://doi.org/10.5194/jbji-9-17-2024, 2024
Short summary
Is ultrasound-guided hip aspiration more successful than fluoroscopic-guided aspiration in diagnosing prosthetic joint infection?
Emily A. Treu, Daniel M. Cushman, John C. Wheelwright, Brenna E. Blackburn, Masaru Teramoto, and Michael J. Archibeck
J. Bone Joint Infect., 8, 151–163, https://doi.org/10.5194/jbji-8-151-2023,https://doi.org/10.5194/jbji-8-151-2023, 2023
Short summary
Simple and inexpensive synovial fluid biomarkers for the diagnosis of prosthetic joint infection according to the new EBJIS definition
Sara Elisa Diniz, Ana Ribau, André Vinha, José Carlos Oliveira, Miguel Araújo Abreu, and Ricardo Sousa
J. Bone Joint Infect., 8, 109–118, https://doi.org/10.5194/jbji-8-109-2023,https://doi.org/10.5194/jbji-8-109-2023, 2023
Short summary
First evaluation of a commercial multiplex PCR panel for rapid detection of pathogens associated with acute joint infections
Jorrit Willem Adriaan Schoenmakers, Rosanne de Boer, Lilli Gard, Greetje Anna Kampinga, Marleen van Oosten, Jan Maarten van Dijl, Paulus Christiaan Jutte, and Marjan Wouthuyzen-Bakker
J. Bone Joint Infect., 8, 45–50, https://doi.org/10.5194/jbji-8-45-2023,https://doi.org/10.5194/jbji-8-45-2023, 2023
Short summary

Cited articles

Auletta, S., Riolo, D., Varani, M., Lauri, C., Galli, F., and Signore, A.: Labelling and Clinical Performance of Human Leukocytes Labelled with 99mTc-HMPAO Using Leukokit® with Gelofusine versus Leukokit® with HES as Sedimentation Agent, Contrast Media Mol. I., 2019, 4368342, https://doi.org/10.1155/2019/4368342, 2019. 
Blanc, P., Bonnet, E., Giordano, G., Monteil, J., Salabert, A., and Payoux, P.: The use of labelled leucocyte scintigraphy to evaluate chronic periprosthetic joint infections: a retrospective multicentre study on 168 patients, Eur. J. Clin. Microbiol. Infect. Dis., 38, 1625–1631, https://doi.org/10.1007/s10096-019-03587-y, 2019. 
Bozhkova, S., Suardi, V., Sharma, H. K., Tsuchiya, H., Del Sel, H., Hafez, M. A., Benzakour, T., Drago, L., and Romanò, C. L.: The W.A.I.O.T. Definition of Peri-Prosthetic Joint Infection: A Multi-center, Retrospective Validation Study, J. Clin. Med., 9, 1965, https://doi.org/10.3390/jcm9061965, 2020. 
de Vries, E. F. J., Roca, M., Jamar, F., Israel, O., and Signore, A.: Guidelines for the labelling of leucocytes with (99m)Tc-HMPAO. Inflammation/Infection Taskgroup of the European Association of Nuclear Medicine, Eur. J. Nucl. Med. Mol. Imaging, 37, 842–848, https://doi.org/10.1007/s00259-010-1394-4, 2010. 
Diaz-Ledezma, C., Lamberton, C., Lichstein, P., and Parvizi, J.: Diagnosis of Periprosthetic Joint Infection: The Role of Nuclear Medicine May Be Overestimated, J. Arthroplasty, 30, 1044–1049, https://doi.org/10.1016/j.arth.2015.01.008, 2015. 
Download
Short summary
A low-grade periprosthetic joint infection (PJI) may be difficult to diagnose, and nuclear imaging could help in the diagnosis. However, its diagnostic value is unclear. We retrospectively evaluated this diagnostic value. We conclude that in patients presenting with nonspecific symptoms and a low a priori chance of PJI based on clinical evaluation, nuclear imaging is of no clear added value in diagnosing a PJI.