Articles | Volume 7, issue 1
J. Bone Joint Infect., 7, 1–9, 2022
https://doi.org/10.5194/jbji-7-1-2022
J. Bone Joint Infect., 7, 1–9, 2022
https://doi.org/10.5194/jbji-7-1-2022

Original full-length article 06 Jan 2022

Original full-length article | 06 Jan 2022

Nuclear imaging does not have clear added value in patients with low a priori chance of periprosthetic joint infection. A retrospective single-center experience

Karsten D. Ottink et al.

Related authors

Black pus from a worn-out elbow arthroplasty
Marjan Wouthuyzen-Bakker and Alexander L. Boerboom
J. Bone Joint Infect., 7, 33–34, https://doi.org/10.5194/jbji-7-33-2022,https://doi.org/10.5194/jbji-7-33-2022, 2022
Short summary
Mid-term clinical results of chronic cavitary long bone osteomyelitis treatment using S53P4 bioactive glass: a multi-center study
Tom A. G. Van Vugt, Jeffrey Heidotting, Jacobus J. Arts, Joris J. W. Ploegmakers, Paul C. Jutte, and Jan A. P. Geurts
J. Bone Joint Infect., 6, 413–421, https://doi.org/10.5194/jbji-6-413-2021,https://doi.org/10.5194/jbji-6-413-2021, 2021
Short summary
The efficacy of suppressive antibiotic treatment in patients managed non-operatively for periprosthetic joint infection and a draining sinus
Karel-Jan Dag François Lensen, Rosa Escudero-Sanchez, Javier Cobo, Rihard Trebše, Camelia Gubavu, Sara Tedeschi, Jose M. Lomas, Cedric Arvieux, Dolors Rodriguez-Pardo, Massimo Fantoni, Maria Jose Garcia Pais, Francisco Jover, Mauro José Costa Salles, Ignacio Sancho, Marta Fernandez Sampedro, Alex Soriano, Marjan Wouthuyzen-Bakker, and ESCMID Study Group of Implant Associated Infections (ESGIAI)
J. Bone Joint Infect., 6, 313–319, https://doi.org/10.5194/jbji-6-313-2021,https://doi.org/10.5194/jbji-6-313-2021, 2021
Short summary
Chronic prosthetic joint infections with a draining sinus. Who should receive suppressive antibiotic treatment?
Karel-Jan Lensen, Rosa Escudero-Sanchez, Javier Cobo, Alex Soriano, and Marjan Wouthuyzen-Bakker
J. Bone Joint Infect., 6, 43–45, https://doi.org/10.5194/jbji-6-43-2020,https://doi.org/10.5194/jbji-6-43-2020, 2020

Related subject area

Subject: Prosthesis-related infections | Topic: Other
Value of ultrasound-guided aspiration of hip arthroplasties performed in an orthopedic clinic by orthopedic surgeons
Holly Duck, Suzanne Tanner, Debra Zillmer, Douglas Osmon, and Kevin Perry
J. Bone Joint Infect., 6, 393–403, https://doi.org/10.5194/jbji-6-393-2021,https://doi.org/10.5194/jbji-6-393-2021, 2021
Short summary

Cited articles

Auletta, S., Riolo, D., Varani, M., Lauri, C., Galli, F., and Signore, A.: Labelling and Clinical Performance of Human Leukocytes Labelled with 99mTc-HMPAO Using Leukokit® with Gelofusine versus Leukokit® with HES as Sedimentation Agent, Contrast Media Mol. I., 2019, 4368342, https://doi.org/10.1155/2019/4368342, 2019. 
Blanc, P., Bonnet, E., Giordano, G., Monteil, J., Salabert, A., and Payoux, P.: The use of labelled leucocyte scintigraphy to evaluate chronic periprosthetic joint infections: a retrospective multicentre study on 168 patients, Eur. J. Clin. Microbiol. Infect. Dis., 38, 1625–1631, https://doi.org/10.1007/s10096-019-03587-y, 2019. 
Bozhkova, S., Suardi, V., Sharma, H. K., Tsuchiya, H., Del Sel, H., Hafez, M. A., Benzakour, T., Drago, L., and Romanò, C. L.: The W.A.I.O.T. Definition of Peri-Prosthetic Joint Infection: A Multi-center, Retrospective Validation Study, J. Clin. Med., 9, 1965, https://doi.org/10.3390/jcm9061965, 2020. 
de Vries, E. F. J., Roca, M., Jamar, F., Israel, O., and Signore, A.: Guidelines for the labelling of leucocytes with (99m)Tc-HMPAO. Inflammation/Infection Taskgroup of the European Association of Nuclear Medicine, Eur. J. Nucl. Med. Mol. Imaging, 37, 842–848, https://doi.org/10.1007/s00259-010-1394-4, 2010. 
Diaz-Ledezma, C., Lamberton, C., Lichstein, P., and Parvizi, J.: Diagnosis of Periprosthetic Joint Infection: The Role of Nuclear Medicine May Be Overestimated, J. Arthroplasty, 30, 1044–1049, https://doi.org/10.1016/j.arth.2015.01.008, 2015. 
Download
Short summary
A low-grade periprosthetic joint infection (PJI) may be difficult to diagnose, and nuclear imaging could help in the diagnosis. However, its diagnostic value is unclear. We retrospectively evaluated this diagnostic value. We conclude that in patients presenting with nonspecific symptoms and a low a priori chance of PJI based on clinical evaluation, nuclear imaging is of no clear added value in diagnosing a PJI.