Articles | Volume 6, issue 8
https://doi.org/10.5194/jbji-6-355-2021
© Author(s) 2021. This work is distributed under
the Creative Commons Attribution 4.0 License.
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/jbji-6-355-2021
© Author(s) 2021. This work is distributed under
the Creative Commons Attribution 4.0 License.
the Creative Commons Attribution 4.0 License.
Left hand extensor tenosynovitis due to Histoplasma capsulatum complicated by immune reconstitution inflammatory syndrome
Division of Infectious Diseases, Mayo Clinic, Rochester, Minnesota, USA
Divisin of Infectious Diseases, University of Arizona Medical Center, Tucson, AZ, USA
Mark Collins
Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA
Mark Enzler
Division of Infectious Diseases, Mayo Clinic, Rochester, Minnesota, USA
Marco Rizzo
Division of Hand Surgery, Mayo Clinic, Rochester, Minnesota, USA
Audrey N. Schuetz
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester,
Minnesota, USA
Julia S. Lehman
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester,
Minnesota, USA
Department of Dermatology, Mayo Clinic, Rochester, Minnesota, USA
Douglas Osmon
Division of Infectious Diseases, Mayo Clinic, Rochester, Minnesota, USA
Irene G. Sia
Division of Infectious Diseases, Mayo Clinic, Rochester, Minnesota, USA
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Short summary
Tenosynovitis due to Histoplasma capsulatum in an immunocompromised host warrants special attention. Following surgical debridement, the patient initially improved on antifungal therapy, but as immunosuppression was decreased, she presented with a flare, requiring further debridement. With negative fungal cultures and declining antigenemia, it was felt that her interim worsening was as a consequence of immune reconstitution inflammatory syndrome (IRIS).
Tenosynovitis due to Histoplasma capsulatum in an immunocompromised host warrants special...