Journal of Bone and Joint Infection
Journal of Bone and Joint Infection
JBJI
Articles | Volume 6, issue 8
Articles | Volume 6, issue 8
https://doi.org/10.5194/jbji-6-355-2021
© Author(s) 2021. This work is distributed under
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/jbji-6-355-2021
© Author(s) 2021. This work is distributed under
the Creative Commons Attribution 4.0 License.
Articles | Volume 6, issue 8
Case report
 | 
23 Sep 2021
Case report |  | 23 Sep 2021

Left hand extensor tenosynovitis due to Histoplasma capsulatum complicated by immune reconstitution inflammatory syndrome

Talha Riaz, Mark Collins, Mark Enzler, Marco Rizzo, Audrey N. Schuetz, Julia S. Lehman, Douglas Osmon, and Irene G. Sia

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Latest update: 13 Dec 2024
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Short summary
Tenosynovitis due to Histoplasma capsulatum in an immunocompromised host warrants special attention. Following surgical debridement, the patient initially improved on antifungal therapy, but as immunosuppression was decreased, she presented with a flare, requiring further debridement. With negative fungal cultures and declining antigenemia, it was felt that her interim worsening was as a consequence of immune reconstitution inflammatory syndrome (IRIS).
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