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Journal of Bone and Joint Infection An open-access journal of the European Bone and Joint Infection Society and the MusculoSkeletal Infection Society
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The aim of this study is to summarize and improve knowledge regarding fracture-related infection caused by Candida (CFRI) through a systematic review on the topic, accompanied by a case report. Candida infections in fractures are rare but difficult-to-treat events. The existing fracture-related infection treatment algorithm combined with long-term systemic antifungal therapy has an anecdotal value and needs more extensive studies to be validated.
JBJI | Articles | Volume 6, issue 7
J. Bone Joint Infect., 6, 321–328, 2021
https://doi.org/10.5194/jbji-6-321-2021
J. Bone Joint Infect., 6, 321–328, 2021
https://doi.org/10.5194/jbji-6-321-2021

Review 23 Aug 2021

Review | 23 Aug 2021

Candida fracture-related infection: a systematic review

Daniele De Meo et al.

Cited articles

Biz, C. and Iacobellis, C.: Nailing treatment in bone transport complications, Strategies Trauma Limb Reconstr., 9, 89–96, https://doi.org/10.1007/s11751-014-0196-9, 2014. 
Brooks, D. H. and Pupparo, F.: Successful salvage of a primary total knee arthroplasty infected with Candida parapsilosis, J. Arthroplasty, 13, 707–712, https://doi.org/10.1016/s0883-5403(98)80017-x, 1998. 
Calori, G. M. and Giannoudis, P. V.: Enhancement of fracture healing with the diamond concept: the role of the biological chamber, Injury, 42, 1191–1193, https://doi.org/10.1016/j.injury.2011.04.016, 2011. 
Cho, K., Lee, S. H., Kim, E. S., and Eoh, W.: Candida parapsilosis spondylodiscitis after lumbar discectomy, J. Korean Neurosurg. Soc., 47, 295–297, https://doi.org/10.3340/jkns.2010.47.4.295, 2010. 
Cobo, F., Rodriguez-Granger, J., Sampedro, A., Aliaga-Martinez, L., and Navarro-Marì, J. M.: Candida Prosthetic Joint Infection. A Review of Treatment Methods, J Bone Jt. Infect., 2, 114–121, https://doi.org/10.7150/jbji.17699, 2017. 
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Short summary
The aim of this study is to summarize and improve knowledge regarding fracture-related infection caused by Candida (CFRI) through a systematic review on the topic, accompanied by a case report. Candida infections in fractures are rare but difficult-to-treat events. The existing fracture-related infection treatment algorithm combined with long-term systemic antifungal therapy has an anecdotal value and needs more extensive studies to be validated.
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