Articles | Volume 11, issue 5
https://doi.org/10.5194/jbji-11-635-2026
© Author(s) 2026. This work is distributed under
the Creative Commons Attribution 4.0 License.
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/jbji-11-635-2026
© Author(s) 2026. This work is distributed under
the Creative Commons Attribution 4.0 License.
the Creative Commons Attribution 4.0 License.
The co-occurrence of peri-prosthetic fracture and infection: a scoping review on current diagnostic principles, treatment and outcome
Noémie Reinert
Center for Musculoskeletal Infections, University Hospital of Basel, Basel, Switzerland
Department of Orthopedic and Trauma Surgery, University Hospital Basel, Basel, Switzerland
Laura Bessems
Department of Trauma Surgery, University Hospitals Leuven, Leuven, Belgium
Department of Development and Regeneration, KU Leuven, Leuven, Belgium
Martin Clauss
Center for Musculoskeletal Infections, University Hospital of Basel, Basel, Switzerland
Department of Orthopedic and Trauma Surgery, University Hospital Basel, Basel, Switzerland
Nader Maai
Center for Musculoskeletal Infections, University Hospital of Basel, Basel, Switzerland
Department of Orthopedic and Trauma Surgery, University Hospital Basel, Basel, Switzerland
Jolien Onsea
Department of Trauma Surgery, University Hospitals Leuven, Leuven, Belgium
Department of Development and Regeneration, KU Leuven, Leuven, Belgium
Georges Vles
Department of Orthopedic Surgery, University Hospitals Leuven, Leuven, Belgium
Karl Stoffel
Department of Orthopedic and Trauma Surgery, University Hospital Basel, Basel, Switzerland
Willem-Jan Metsemakers
Department of Trauma Surgery, University Hospitals Leuven, Leuven, Belgium
Department of Development and Regeneration, KU Leuven, Leuven, Belgium
Mario Morgenstern
CORRESPONDING AUTHOR
Center for Musculoskeletal Infections, University Hospital of Basel, Basel, Switzerland
Department of Orthopedic and Trauma Surgery, University Hospital Basel, Basel, Switzerland
Latest update: 14 Oct 2026
Short summary
Infected periprosthetic fractures are severe complications in orthopedic surgery with difficult management and high failure rates. This review of 32 studies (273 patients) found limited diagnostic reliability, frequent use of staged revision surgery, and high rates of recurrent infection (21 %) and revision surgeries. Current evidence is sparse and inconsistent, highlighting the need for standardized diagnostics and larger-prospective studies.
Infected periprosthetic fractures are severe complications in orthopedic surgery with difficult...