Journal of Bone and Joint Infection
Journal of Bone and Joint Infection
JBJI
Articles | Volume 11, issue 4
Articles | Volume 11, issue 4
https://doi.org/10.5194/jbji-11-441-2026
© Author(s) 2026. This work is distributed under
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/jbji-11-441-2026
© Author(s) 2026. This work is distributed under
the Creative Commons Attribution 4.0 License.
Articles | Volume 11, issue 4
Review
 | 
28 Jul 2026
Review |  | 28 Jul 2026

Bromelain and N-acetylcysteine (BromAc) as novel adjunctive therapy for prosthetic joint infection: a narrative review

Brendan Parnell and David Morris

Viewed

Total article views: 667 (including HTML, PDF, and XML)
HTML PDF XML Total BibTeX EndNote
473 161 33 667 32 37
  • HTML: 473
  • PDF: 161
  • XML: 33
  • Total: 667
  • BibTeX: 32
  • EndNote: 37
Views and downloads (calculated since 28 Jul 2026)
Cumulative views and downloads (calculated since 28 Jul 2026)

Viewed (geographical distribution)

Total article views: 613 (including HTML, PDF, and XML) Thereof 613 with geography defined and 0 with unknown origin.
Country # Views %
  • 1
1
 
 
 
 
Latest update: 27 Oct 2026
Download
Short summary
Prosthetic joint infections are devastating complications of joint replacements, often resisting antibiotics because bacteria hide inside a protective slime called biofilm. We reviewed laboratory evidence on BromAc, a combination of a pineapple enzyme and a mucus-thinning agent that breaks down this slime. Early experiments suggest it can disrupt biofilm and improve antibiotic access, but key questions about safety, stability, and joint-specific testing must be answered before patient use.
Read more
Share