We looked at whether routine blood tests could help identify patients at higher risk of infection after hip fracture surgery. Using data from a large group of older patients, we found that higher inflammation levels after surgery, especially when they increased compared to before surgery, were linked to a greater risk of infection. This suggests that simple and widely available tests may help clinicians recognize high-risk patients earlier and guide closer follow-up.

Fungal infection can be difficult to treat, requiring long periods of hospitalisation. Rezafungin is a promising new antifungal medication that can be used to treat complex, deep-seated fungal infection. We examine the reported use of rezafungin in managing fungal infection of the bones and joints in an outpatient setting. Our case helps to provide further experience in the use of rezafungin as a powerful tool in helping patients get out of hospital and avoid further admissions.

Fracture-related infection is a serious problem after broken bones, especially in low-resource settings where specialist care and services are limited. An international expert group developed practical recommendations adapted to these realities. The guidance focuses on early fracture care, simple diagnostic approaches, flexible antibiotic use, affordable local treatments, good soft tissue management, and teamwork, aiming to improve safe and effective care in resource-limited environments.

Culture-negative periprosthetic joint infection (CN-PJI) remains a diagnostic and therapeutic challenge. In this systematic review and meta-analysis of 27 studies (1399 patients), pooled success was 83.6 %, failure was 17.2 %, and mortality was 2.4 %. Outcomes were better with exchange arthroplasty than debridement, antimicrobials, and implant retention (DAIR). Antibiotic regimens were heterogeneous. Overall, CN-PJI may have favorable outcomes, but standardized prospective studies are needed.

This study explores the diagnostic value of sonication fluid culture (SFC) as an adjunct to conventional diagnostic methods for fracture-related infection (FRI). SFC improves pathogen detection and contributes to more accurate diagnosis of FRI. In approximately 6 % to 16 % of confirmed FRI cases, SFC influenced FRI management. These findings support the routine use of SFC alongside standard tissue cultures, with adequate sampling according to protocol.