Articles | Volume 11, issue 4
https://doi.org/10.5194/jbji-11-387-2026
https://doi.org/10.5194/jbji-11-387-2026
Original full-length article
 | 
03 Jul 2026
Original full-length article |  | 03 Jul 2026

Changes in systemic immune–inflammation index predict periprosthetic joint infection after hemiarthroplasty in elderly patients

Emre Bilgin, Onur Gultekin, Murat Kilic, Umit Burak Alparslan, Mehmet Berke Yusan, and Ahmet Onur Akpolat

Cited articles

Alsabani, M. H., Alotaibi, B. A., Olayan, L. H., Alghamdi, A. S., Alshammasi, M. A., Alqasir, B. A., Alrashidi, S. M., Alshugair, M. S., and Al Harbi, M. K.: The value of preoperative systemic immune-inflammation index as a predictor of prolonged hospital stay in orthopedic surgery: a retrospective study, Int. J. Gen. Med., 16, 4773–4782, https://doi.org/10.2147/IJGM.S434630, 2023. 
Bingham, J. S., Salib, C. G., McQuivey, K., Temkit, M., and Spangehl, M. J.: An evidence-based clinical prediction algorithm for the Musculoskeletal Infection Society minor criteria, J. Arthroplasty, 33, 2993–2996, https://doi.org/10.1016/j.arth.2018.04.047, 2018. 
Casqueiro, J., Casqueiro, J., and Alves, C.: Infections in patients with diabetes mellitus: a review of pathogenesis, Indian J. Endocrinol. Metab., 16, S27–S36, https://doi.org/10.4103/2230-8210.94253, 2012. 
Chang, W. P. and Peng, Y. X.: Differences between patients with diabetes mellitus and obese patients in occurrence of peri-prosthetic joint infection: a systematic review and meta-analysis, Surg. Infect. (Larchmt), 24, 671–683, https://doi.org/10.1089/sur.2023.139, 2023. 
Chou, C.-M., Chuang, T.-C., and Chiang, C.-H.: Factors that increase the risk of prosthetic joint infection within 90 days after THA and TKA: a nationwide population-based study, Clin. Orthop. Relat. Res., 484, 109–116, https://doi.org/10.1097/CORR.0000000000003592, 2026. 
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Short summary
We looked at whether routine blood tests could help identify patients at higher risk of infection after hip fracture surgery. Using data from a large group of older patients, we found that higher inflammation levels after surgery, especially when they increased compared to before surgery, were linked to a greater risk of infection. This suggests that simple and widely available tests may help clinicians recognize high-risk patients earlier and guide closer follow-up.
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