Articles | Volume 11, issue 3
https://doi.org/10.5194/jbji-11-363-2026
© Author(s) 2026. This work is distributed under
the Creative Commons Attribution 4.0 License.
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/jbji-11-363-2026
© Author(s) 2026. This work is distributed under
the Creative Commons Attribution 4.0 License.
the Creative Commons Attribution 4.0 License.
Original full-length article
| 
22 Jun 2026
Original full-length article |
| 22 Jun 2026
| 22 Jun 2026
Neutrophil extracellular trap (NET)-related index as an indicator of periprosthetic joint infection
Tingrun Cui
Department of Orthopaedics and Traumatology, Beijing Jishuitan Hospital, Capital Medical University, Beijing, 100035, China
National Center for Orthopaedics, Beijing, 100035, China
Yongjian Liang
Department of Orthopaedics, the First Medical Center of Chinese PLA General Hospital, Beijing, 100053, China
Senior Department of Orthopaedics, the Fourth Medical Center of Chinese PLA General Hospital, Beijing, 100048, China
Zeyu Feng
Department of Orthopaedics, the First Medical Center of Chinese PLA General Hospital, Beijing, 100053, China
Senior Department of Orthopaedics, the Fourth Medical Center of Chinese PLA General Hospital, Beijing, 100048, China
Libo Hao
Department of Orthopaedics, the First Medical Center of Chinese PLA General Hospital, Beijing, 100053, China
Senior Department of Orthopaedics, the Fourth Medical Center of Chinese PLA General Hospital, Beijing, 100048, China
Guoqiang Zhang
Department of Orthopaedics, the First Medical Center of Chinese PLA General Hospital, Beijing, 100053, China
Senior Department of Orthopaedics, the Fourth Medical Center of Chinese PLA General Hospital, Beijing, 100048, China
Ming Ni
Department of Orthopaedics, the First Medical Center of Chinese PLA General Hospital, Beijing, 100053, China
Senior Department of Orthopaedics, the Fourth Medical Center of Chinese PLA General Hospital, Beijing, 100048, China
Jing Sheng
Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Bio-systems, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, China
School of Chemical Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China
Dihua Shangguan
Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Bio-systems, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, China
School of Chemical Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China
Jiying Chen
CORRESPONDING AUTHOR
Department of Orthopaedics, the First Medical Center of Chinese PLA General Hospital, Beijing, 100053, China
Senior Department of Orthopaedics, the Fourth Medical Center of Chinese PLA General Hospital, Beijing, 100048, China
Jun Fu
CORRESPONDING AUTHOR
Department of Orthopaedics, the First Medical Center of Chinese PLA General Hospital, Beijing, 100053, China
Senior Department of Orthopaedics, the Fourth Medical Center of Chinese PLA General Hospital, Beijing, 100048, China
Latest update: 22 Jun 2026
Short summary
Periprosthetic joint infection is the most challenging complication following arthroplasty. This study, utilizing clinically obtained synovial fluid specimens, confirmed the unique value of neutrophil extracellular traps and their constituent components in the diagnosis of periprosthetic joint infection, thereby enabling further precision in the diagnosis of periprosthetic joint infection and reducing the severe consequences associated with it.
Periprosthetic joint infection is the most challenging complication following arthroplasty. This...
