Journal of Bone and Joint Infection
Journal of Bone and Joint Infection
JBJI
Articles | Volume 11, issue 1
Articles | Volume 11, issue 1
https://doi.org/10.5194/jbji-11-31-2026
© Author(s) 2026. This work is distributed under
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/jbji-11-31-2026
© Author(s) 2026. This work is distributed under
the Creative Commons Attribution 4.0 License.
Articles | Volume 11, issue 1
Original full-length article
 | 
13 Jan 2026
Original full-length article |  | 13 Jan 2026

The proportion of chronic periprosthetic joint infection patients with Candida isolates

Samuelson E. Osifo, Adrian Santana, Michael F. Shannon, Victoria R. Wong, Caroline F. Tyndall, Christian Cisneros, Niosha Parvizi, Brian A. Klatt, Johannes F. Plate, Nicolas S. Piuzzi, and Kenneth L. Urish

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Short summary
Fungal organisms are conventionally estimated to account for 1 % –2 % of periprosthetic joint infection (PJI) cases, although diagnostic and reporting limitations may result in systematic underestimation. Using a quantitative missing-data sensitivity analysis across 23 studies encompassing 28 253 PJI cases, we estimated an adjusted Candida PJI proportion of approximately 5 %, increasing to nearly 10 % in chronic or refractory infections.
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