Articles | Volume 11, issue 1
https://doi.org/10.5194/jbji-11-123-2026
https://doi.org/10.5194/jbji-11-123-2026
Original full-length article
 | 
25 Feb 2026
Original full-length article |  | 25 Feb 2026

Septic arthritis and prosthetic joint infections: microbial spectrum and evolving resistance patterns

Merve Gürler, Füsun Kırca, and Bedia Dinç

Cited articles

Abdeta, A., Negeri, A. A., Beyene, D., Adamu, E., Fekede, E., Fentaw, S., Tesfaye, M., and Wakoya, G. K.: Prevalence and trends of carbapenem-resistant Pseudomonas aeruginosa and Acinetobacter species isolated from clinical specimens at the Ethiopian public health institute, Addis Ababa, Ethiopia: A Retrospective Analysis, Infect. Drug Resist., 1381–1390, https://doi.org/10.2147/IDR.S403360, 2023. 
Alexandersson, H., Dehlin, M., and Jin, T.: Increased incidence and clinical features of septic arthritis in patients aged 80 years and above: a comparative analysis with younger cohorts, Pathogens, 13, 891, https://doi.org/10.3390/pathogens13100891, 2024. 
Ali Khan, M., Kamran Taj, M., Khan, Z., Taj, I., Naeem, M., and Azam, S.: Escherichia coli in septic arthritis: prevalence and antibiotics susceptibility patterns, Iran J. Microbiol., 17, 25–31, https://doi.org/10.18502/ijm.v17i1.17798, 2025. 
Arieli, M. M., Fowler, M. L., Lieber, S. B., Shmerling, R. H., and Paz, Z.: The profile of the causative organisms which lead to septic arthritis of native joints over the last two decades in a single tertiary medical center in the east coast of the United States, Int. J. Clin. Pract., 75, e15003, https://doi.org/10.1111/ijcp.15003, 2021. 
Ayoade, F., Li, D., Mabrouk, A., and Todd, J. R.: Periprosthetic joint infection, in: StatPearls [Internet], StatPearls Publishing, https://www.ncbi.nlm.nih.gov/books/NBK448131/ (last access: 24 February 2026), 2023. 
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Short summary
This study examined thousands of joint fluid samples to understand which bacteria cause infections in natural and artificial joints. Staphylococci were the main culprits, and antibiotic resistance increased over time, especially in methicillin-resistant and beta-lactamase-producing strains. Testing joint fluids in blood culture bottles improved detection, helping doctors to choose more effective treatments and protect joint health.
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