Journal of Bone and Joint Infection
Journal of Bone and Joint Infection
JBJI
Articles | Volume 9, issue 6
Articles | Volume 9, issue 6
https://doi.org/10.5194/jbji-9-261-2024
© Author(s) 2024. This work is distributed under
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/jbji-9-261-2024
© Author(s) 2024. This work is distributed under
the Creative Commons Attribution 4.0 License.
Articles | Volume 9, issue 6
Original full-length article
 | 
07 Nov 2024
Original full-length article |  | 07 Nov 2024

The immediate ex vivo covering and filling characteristics of antibiotic-loaded resorbable calcium sulfate paste around intramedullary nails

Amber A. Hamilton, Jidapa Wongcharoenwatana, Jason S. Hoellwarth, Austin T. Fragomen, S. Robert Rozbruch, and Taylor J. Reif

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Latest update: 13 Sep 2026
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Short summary
Implant-related osteomyelitis is common in orthopedics. Absorbable antibiotic-loaded calcium sulfate (ACS) is an alternative to nonabsorbable antibiotic depot options for osteomyelitis and fracture-related infections. This study aims to evaluate intramedullary canal filling and coating characteristics of ACS around tibial nails using a tibia SAWBONES model. This research was done to better understand the potential utility of ACS in situations requiring fixation in the setting of local infection.
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