Articles | Volume 9, issue 5
https://doi.org/10.5194/jbji-9-213-2024
https://doi.org/10.5194/jbji-9-213-2024
Case report
 | 
07 Oct 2024
Case report |  | 07 Oct 2024

Efficacy of rezafungin in a case of Candida spondylodiskitis

Marin Lahouati, Claire Tinévez, Frédéric Gabriel, Fabien Xuereb, Maxime Lefranc, and Frédéric-Antoine Dauchy

Cited articles

Desnos-Ollivier, M., Lortholary, O., Bretagne, S., and Dromer, F.: Azole Susceptibility Profiles of More than 9,000 Clinical Yeast Isolates Belonging to 40 Common and Rare Species, Antimicrob. Agents Chemother., 65, e02615-20, https://doi.org/10.1128/AAC.02615-20, 2021.  
Gamaletsou, M. N., Kontoyiannis, D. P., Sipsas, N. V., Moriyama, B., Alexander, E., Roilides, E., Brause, B., and Walsh, T. J.: Candida Osteomyelitis: Analysis of 207 Pediatric and Adult Cases (1970–2011), Clin. Infect. Dis., 55, 1338–1351, https://doi.org/10.1093/cid/cis660, 2012. 
Pfaller, M. A., Messer, S. A., Rhomberg, P. R., Jones, R. N., and Castanheira, M.: Activity of a long-acting echinocandin, CD101, determined using CLSI and EUCAST reference methods, against Candida and Aspergillus spp., including echinocandin- and azole-resistant isolates, J. Antimicrob. Chemother., 71, 2868–2873, https://doi.org/10.1093/jac/dkw214, 2016. 
Sandison, T., Ong, V., Lee, J., and Thye, D.: Safety and Pharmacokinetics of CD101 IV, a Novel Echinocandin, in Healthy Adults, Antimicrob. Agents Chemother., 61, e01627-16, https://doi.org/10.1128/AAC.01627-16, 2017. 
Download
Short summary
This work outlines the first case study of Candida glabrata bone and joint infection successfully treated with 3 weeks of caspofungin followed by 10 weeks of rezafungin, a new generation of antifungal treatment, using a weekly administration mode.