Articles | Volume 9, issue 4
https://doi.org/10.5194/jbji-9-197-2024
https://doi.org/10.5194/jbji-9-197-2024
Case report
 | 
25 Jul 2024
Case report |  | 25 Jul 2024

Musculoskeletal manifestations of lower-extremity coccidioidomycosis: a case series

William Estes, L. Daniel Latt, Jacob Robishaw-Denton, Matthew L. Repp, Yash Suri, Tyson Chadaz, Christina Boulton, and Talha Riaz

Related subject area

Subject: Microbiology of bone and joint infections | Topic: All topics
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Cited articles

Ahmad, F., Patel, K., De Leon, J. C., and Buttacavoli, F. A.: Disseminated Coccidioidomycosis of the Knee Joint Requiring Synovectomy and Arthrotomy, J. Orthop. Case Rep., 2, 76–80, 2021. 
Ampel, N. M.: Coccidioidomycosis in persons infected with HIV-1, Ann. NY Acad. Sci., 1111, 336–342, https://doi.org/10.1196/annals.1406.033, 2007. 
Ampel, N. M., Giblin, A., Mourani, J. P., and Galgiani, J. N.: Factors and outcomes associated with the decision to treat primary pulmonary coccidioidomycosis, Clin. Infect. Dis., 48, 172–178, 2009. https://doi.org/10.1086/595687, 2009. 
Antony, S. J., Parikh, M. S., and Friedman, G.: Coccidioidomycosis involving the cranium: a case report and review of current literature, Infect. Disord. Drug Targets, 15, 202–206, https://doi.org/10.2174/1871526515666150724101823, 2015. 
Blair, J. E.: State-of-the-art treatment of coccidioidomycosis skeletal infections, Ann. NY Acad. Sci., 1111, 422–433, https://doi.org/10.1196/annals.1406.000, 2007. 
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Short summary
Musculoskeletal coccidioidomycosis can present in a variety of ways and often mimics non-infectious disease processes, making timely diagnosis challenging. Missed diagnosis can lead to devastating consequences, including joint destruction. Treatment often involves surgical debridement and prolonged antifungal therapy. Physicians in endemic areas should have a low threshold for obtaining Coccidioides-specific labs when patients present with unexplained musculoskeletal complaints.