Articles | Volume 9, issue 3
https://doi.org/10.5194/jbji-9-173-2024
https://doi.org/10.5194/jbji-9-173-2024
Review
 | 
24 Jun 2024
Review |  | 24 Jun 2024

It is time for a unified definition of native vertebral osteomyelitis: a framework proposal

Francesco Petri, Omar Mahmoud, Said El Zein, Ahmad Nassr, Brett A. Freedman, Jared T. Verdoorn, Aaron J. Tande, and Elie F. Berbari

Related authors

Optimal antibiotics duration following surgical management of septic olecranon bursitis: a 12-year retrospective analysis
Said El Zein, Elie F. Berbari, Allison M. LeMahieu, Anil Jagtiani, Parham Sendi, Abinash Virk, Mark E. Morrey, and Aaron J. Tande
J. Bone Joint Infect., 9, 107–115, https://doi.org/10.5194/jbji-9-107-2024,https://doi.org/10.5194/jbji-9-107-2024, 2024
Short summary
Characteristics and management of periprosthetic joint infections caused by rapidly growing mycobacteria: a retrospective study and a review of the literature
Pansachee Damronglerd, Eibhlin Higgins, Madiha Fida, Don Bambino Geno Tai, Aaron J. Tande, Matthew P. Abdel, and Omar M. Abu Saleh
J. Bone Joint Infect., 9, 99–106, https://doi.org/10.5194/jbji-9-99-2024,https://doi.org/10.5194/jbji-9-99-2024, 2024
Short summary
Cutibacterium acnes in spine tissue: characteristics and outcomes of non-hardware-associated vertebral osteomyelitis
Matteo Passerini, Julian Maamari, Don Bambino Geno Tai, Robin Patel, Aaron J. Tande, Zelalem Temesgen, and Elie F. Berbari
J. Bone Joint Infect., 8, 143–149, https://doi.org/10.5194/jbji-8-143-2023,https://doi.org/10.5194/jbji-8-143-2023, 2023
Short summary
Sex-specific analysis of clinical features and outcomes in staphylococcal periprosthetic joint infections managed with two-stage exchange arthroplasty
Eibhlin Higgins, Don Bambino Geno Tai, Brian Lahr, Gina A. Suh, Elie F. Berbari, Kevin I. Perry, Matthew P. Abdel, and Aaron J. Tande
J. Bone Joint Infect., 8, 125–131, https://doi.org/10.5194/jbji-8-125-2023,https://doi.org/10.5194/jbji-8-125-2023, 2023
Short summary
Early switch to oral antibiotic therapy for the treatment of patients with bacterial native vertebral osteomyelitis: a quaternary center experience, systematic review, and meta-analysis
Matteo Passerini, Julian Maamari, Tarek Nayfeh, Leslie C. Hassett, Aaron J. Tande, Mohammad H. Murad, Zelalem Temesgen, and Elie F. Berbari
J. Bone Joint Infect., 7, 249–257, https://doi.org/10.5194/jbji-7-249-2022,https://doi.org/10.5194/jbji-7-249-2022, 2022
Short summary

Related subject area

Subject: Spinal infections | Topic: All topics
Vertebral osteomyelitis with Campylobacter jejuni – a case report and review of the literature of a very rare disease
Simone Greminger, Carol Strahm, Julia Notter, Benjamin Martens, Seth Florian Helfenstein, Jürgen Den Hollander, and Manuel Frischknecht
J. Bone Joint Infect., 9, 59–65, https://doi.org/10.5194/jbji-9-59-2024,https://doi.org/10.5194/jbji-9-59-2024, 2024
Short summary
Pyogenic spinal infections warrant a total spine MRI
Cristian Balcescu, Khalid Odeh, Alexander Rosinski, Brandon Nudelman, Adam Schlauch, Ishan Shah, Victor Ungurean Jr., Priya Prasad, Jeremi Leasure, Flora Stepansky, Amit Piple, and Dimitriy Kondrashov
J. Bone Joint Infect., 8, 1–9, https://doi.org/10.5194/jbji-8-1-2023,https://doi.org/10.5194/jbji-8-1-2023, 2023
Short summary
A sticky situation: a case of Actinomyces viscosus vertebral osteomyelitis
Stephanie L. Grach and Aaron J. Tande
J. Bone Joint Infect., 6, 39–42, https://doi.org/10.5194/jbji-6-39-2020,https://doi.org/10.5194/jbji-6-39-2020, 2020

Cited articles

Alonso-Coello, P., Schünemann, H. J., Moberg, J., Brignardello-Petersen, R., Akl, E. A., Davoli, M., Treweek, S., Mustafa, R. A., Rada, G., Rosenbaum, S., Morelli, A., Guyatt, G. H., and Oxman, A. D.: GRADE Working Group: GRADE Evidence to Decision (EtD) frameworks: a systematic and transparent approach to making well informed healthcare choices. 1: Introduction, BMJ, 353, i2016, https://doi.org/10.1136/bmj.i2016, 2016. 
Babic, M. and Simpfendorfer, C. S.: Infections of the Spine, Infect. Dis. Clin. North. Am., 31, 279–297, https://doi.org/10.1016/j.idc.2017.01.003, 2017. 
Berbari, E. F., Kanj, S. S., Kowalski, T. J., Darouiche, R. O., Widmer, A. F., Schmitt, S. K., Hendershot, E. F., Holtom, P. D., Huddleston III, P. M., Petermann, G. W., Osmon, D. R., and Infectious Diseases Society of America: 2015 Infectious Diseases Society of America (IDSA) Clinical Practice Guidelines for the Diagnosis and Treatment of Native Vertebral Osteomyelitis in Adults, Clin. Infect. Dis., 61, e26–46, https://doi.org/10.1093/cid/civ482, 2015. 
Bernard, L., Dinh, A., Ghout, I., Simo, D., Zeller, V., Issartel, B., Le Moing, V., Belmatoug, N., Lesprit, P., Bru, J. P., Therby, A., Bouhour, D., Denes, E., Debard, A., Chirouze, C., Fevre, K., Dupon, M., Aegerter, P., Mulleman, D., and Duration of Treatment for Spondylodiscitis (DTS) study group: Antibiotic treatment for six weeks versus 12 weeks in patients with pyogenic vertebral osteomyelitis: an open-label, non-inferiority, randomised, controlled trial, Lancet, 385, 875–882, https://doi.org/10.1016/S0140-6736(14)61233-2, 2015. 
Boisrenoult, P.: Cutibacterium acnes prosthetic joint infection: Diagnosis and treatment, Orthop. Traumatol. Surg. Res., 104, S19–S24, https://doi.org/10.1016/j.otsr.2017.05.030, 2018. 
Download
Short summary
In recent years, there has been an increase in scientific production on native vertebral osteomyelitis (NVO), a condition whose incidence is rising and that can be highly detrimental to health. However, there is no consensus on the definition of this syndrome in the medical community. Therefore, we propose a new framework to synthesize the diagnostic tools at our disposal. This can help to advance research further and guide patient care more effectively.