Journal of Bone and Joint Infection
Journal of Bone and Joint Infection
JBJI
Articles | Volume 8, issue 2
Articles | Volume 8, issue 2
https://doi.org/10.5194/jbji-8-91-2023
© Author(s) 2023. This work is distributed under
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/jbji-8-91-2023
© Author(s) 2023. This work is distributed under
the Creative Commons Attribution 4.0 License.
Articles | Volume 8, issue 2
Original full-length article
 | 
22 Mar 2023
Original full-length article |  | 22 Mar 2023

The efficacy of antibiotic-impregnated calcium sulfate (AICS) in the treatment of infected non-union and fracture-related infection: a systematic review

Connor C. Jacob, Jad H. Daw, and Juan Santiago-Torres

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Latest update: 21 Nov 2024
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Short summary
Sometimes after surgery to repair an injured bone or joint, infection can cause the bone to heal improperly. Surgeons use calcium sulfate to prevent infections in joints after surgery. Calcium sulfate can be impregnated with antibiotics and placed inside the joint, where the bloodstream often cannot deliver intravenous or oral antibiotics effectively. We reviewed 20 years of studies of the effectiveness of calcium sulfate and found high rates of healing and infection eradication.
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