Articles | Volume 8, issue 4
https://doi.org/10.5194/jbji-8-183-2023
https://doi.org/10.5194/jbji-8-183-2023
Case report
 | 
02 Aug 2023
Case report |  | 02 Aug 2023

A natural history of untreated chronic osteomyelitis of the tibia over 20 years, with evolving squamous cell carcinoma: a case report

Asanka Wijendra, Alex Ramsden, and Martin McNally

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Short summary

Cancerous transformation is a rare but potentially life-threatening complication of chronic bone infection. As with all forms of cancer, early detection and diagnosis is crucial to outcome.

Whilst there have been over 100 cases of chronic bone infection with cancerous transformation reported in the literature between 1999 and 2020, this is the first case report to document transformation with 20 years of concordant imaging and clinical review.