Articles | Volume 8, issue 3
21 Jun 2023
Review |  | 21 Jun 2023

The antibiotic bead pouch – a useful technique for temporary soft tissue coverage, infection prevention and therapy in trauma surgery

Markus Rupp, Nike Walter, Dominik Szymski, Christian Taeger, Martin Franz Langer, and Volker Alt

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Cited articles

Behrend, R.: Gentamicin-polymethylmethacrylate chains in the treatment of infected cardiac pacemaker pouches – two case reports, Recons. Surg., 20, 101–104, 1988. 
Bowyer, G.: Antibiotic impregnated beads in open fractures. A report on the technique and possible applications in military surgery, BMJ Military Health, 139, 100–104, 1993. 
Bratzler, D. W. and Houck, P. M.: Antimicrobial prophylaxis for surgery: an advisory statement from the National Surgical Infection Prevention Project, Clin. Infect. Dis., 38, 1706–1715, 2004. 
Buchholz, H.: Uber die Depotwirkung einiger Antibiotika bei Vermischung mit dem Kunstharz Palacos, Chirurg, 40, 511–515, 1970. 
Chaudhary, S., Sen, R., Saini, U. C., Soni, A., Gahlot, N., and Singh, D.: Use of gentamicin-loaded collagen sponge in internal fixation of open fractures, Chinese Journal of Traumatology, 14, 209–214, 2011. 
Short summary
The antibiotic bead pouch is a useful technique for temporary soft tissue coverage. After the introduction of negative wound pressure therapy, it has fallen into oblivion. However, the technique has several advantages, which are highlighted in the present review article. After debridement, the antibiotic beads deliver high dosages of antibiotics suitable for bone cements. This enables a sterile wound, which might help to avoid either infection or progress of infection.