Articles | Volume 7, issue 2
https://doi.org/10.5194/jbji-7-91-2022
https://doi.org/10.5194/jbji-7-91-2022
Original full-length article
 | 
20 Apr 2022
Original full-length article |  | 20 Apr 2022

Standardized quantification of biofilm in a novel rabbit model of periprosthetic joint infection

Anabelle Visperas, Daniel Santana, Minseon Ju, Nathalie B. Milbrandt, Yu Hsin Tsai, Sameera Wickramasinghe, Alison K. Klika, Nicolas S. Piuzzi, Anna Cristina S. Samia, and Carlos A. Higuera-Rueda

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Latest update: 13 Dec 2024
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Short summary
Periprosthetic joint infection (PJI) is a complication of total joint arthroplasty, and treatment failure rates are still quite high. This study has developed a novel rabbit model of PJI that provides an opportunity to introduce treatments during ongoing infection, with readouts including a quantifiable method to assess biofilm coverage on implants via scanning electron microscopy (SEM).