Articles | Volume 7, issue 4
https://doi.org/10.5194/jbji-7-177-2022
https://doi.org/10.5194/jbji-7-177-2022
Original full-length article
 | 
08 Aug 2022
Original full-length article |  | 08 Aug 2022

A comparison of the microbiology profile for periprosthetic joint infection of knee arthroplasty and lower-limb endoprostheses in tumour surgery

Robert A. McCulloch, Amirul Adlan, Neil Jenkins, Michael Parry, Jonathan D. Stevenson, and Lee Jeys

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Cited articles

Bosco, J. A., Bookman, J., Slover, J., Edusei, E., and Levine, B.: Principles of antibiotic prophylaxis in total joint arthroplasty: current concepts, J. Am. Acad. Orthoph. Sur., 1, 27–35, 2015. 
Christensen, D. D., Moschetti, W. E., Brown, M. G., Lucas, A. P., Jevsevar, D. S., Fillingham, Y. A., and Center, D. H.: Perioperative Antibiotic Prophylaxis: Single and 24-Hour Antibiotic Dosages are Equally Effective at Preventing Periprosthetic Joint Infection in Total Joint Arthroplasty, J. Arthroplasty, 1, 308–313, 2021. 
Cirstoiu, C., Cretu, B., Serban, B., Panti, Z., and Nica, M.: Current review of surgical management options for extremity bone sarcomas, EFORT open reviews, 4, 174–182, 2019. 
Dhanoa, A., Ajit Singh, V., and Elbahri, H.: Deep infections after endoprosthetic replacement operations in orthopedic oncology patients, Surg. Infect. (Larchmt)., 16, 323–332, 2015. 
Fehring, K. A., Abdel, M. P., Ollivier, M., Mabry, T. M., and Hanssen, A. D.: Repeat two-stage exchange arthroplasty for periprosthetic knee infection is dependent on host grade, J. Bone Joint. Surg. Am., 4, 19–24, 2017. 
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Short summary
This paper displays the microbiological differences between infected endoprostheses post tumour resection and infected primary knee arthroplasty. It emphasises the point that significant differences between the two groups, including higher rates of multidrug resistant organisms in the endoprosthetic group, point to the requirement for the pre-emptive use of broad-spectrum empirical antibiotics. Pre-surgical sampling or aspiration is also of particular importance in the endoprosthetic group.