Articles | Volume 7, issue 4
J. Bone Joint Infect., 7, 155–162, 2022
J. Bone Joint Infect., 7, 155–162, 2022
Original full-length article
18 Jul 2022
Original full-length article | 18 Jul 2022

Unexpected positive intraoperative cultures (UPIC) at index osseointegration do not lead to increased postoperative infectious events

Jason S. Hoellwarth et al.

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Cited articles

Agrawal, A., Chauhan, V. D., Maheshwari, R. K., and Juyal, A. K.: Primary Nailing in the Open Fractures of the Tibia – Is it worth?, J. Clin. Diagn. Res., 7, 1125–1130, 2013. 
Al Muderis, M., Lu, W., Tetsworth, K., Bosley, B., and Li, J. J.: Single-stage osseointegrated reconstruction and rehabilitation of lower limb amputees: The Osseointegration Group of Australia Accelerated Protocol-2 (OGAAP-2) for a prospective cohort study, BMJ Open, 7, e013508,, 2017. 
Atallah, R., van de Meent, H., Verhamme, L., Frölke, J. P., and Leijendekkers, R. A.: Safety, prosthesis wearing time and health-related quality of life of lower extremity bone-anchored prostheses using a press-fit titanium osseointegration implant: A prospective one-year follow-up cohort study, PLoS One, 15, 1–18, 2020. 
Bemben, D. A., Sherk, V. D., Ertl, W. J. J., and Bemben, M. G.: Acute bone changes after lower limb amputation resulting from traumatic injury, Osteoporos. Int., 28, 2177–2186, 2017. 
Carlsson, A. K., Lidgren, L., and Lindberg, L.: Prophylactic antibiotics against early and late deep infections after total hip replacements, Acta Orthop. Scand., 48, 405–410, 1977. 
Short summary
The stoma for transcutaneous osseointegration carries a permanent source of bacterial ingress and infection. The value and role of intraoperative cultures to detect latent bacterial contamination or infection with targeted postoperative antibiotics has not been previously investigated. We compared two cohorts, 8 patients with unexpected positive cultures and 22 patients with negative intraoperative cultures, and found positive cultures do not appear to portend future infectious events.