Brooks, J. R., Dusane, D. H., Moore, K., Gupta, T., Delury, C., Aiken, S. S., Laycock, P. A., Sullivan, A. C., Granger, J. F., Dipane, M. V., McPherson, E. J., and Stoodley, P.:
Pseudomonas aeruginosa biofilm killing beyond the spacer by antibiotic-loaded calcium sulfate beads: an in vitro study, J. Bone Joint Infect., 6, 119–129, https://doi.org/10.5194/jbji-6-119-2021, 2021.
Costerton, J. W., Stewart, P. S., and Greenberg, E. P.: Bacterial
biofilms: a common cause of persistent infections, Science, 284,
1318–1322, https://doi.org/10.1126/science.284.5418.1318, 1999.
Ferguson, J. Y., Dudareva, M., Riley, N. D., Stubbs, D., Atkins, B. L.,
and McNally, M. A.: The use of a biodegradable antibiotic-loaded calcium
sulphate carrier containing tobramycin for the treatment of chronic
osteomyelitis: a series of 195 cases, Bone Joint J., 96-B, 829–836, https://doi.org/10.1302/0301-620X.96B6.32756, 2014.
Grimsrud, C., Raven, R., Fothergill, A. W., and Kim, H. T.: The in vitro
elution characteristics of antifungal-loaded PMMA bone cement and calcium
sulfate bone substitute, Orthopedics, 34, e378-81, https://doi.org/10.3928/01477447-20110627-05, 2011.
Hamad, C., Chowdhry, M., Sindeldecker, D., Bernthal, N. M., Stoodley, P.,
and McPherson, E. J.: Adaptive antimicrobial resistance, a description of
microbial variants, and their relevance to periprosthetic joint infection,
Bone Joint J., 104-B, 575–580, https://doi.org/10.1302/0301-620X.104B5.BJJ-2021-1759.R1, 2022.
Kallala, R. and Haddad, F. S.: Hypercalcaemia following the use of
antibiotic-eluting absorbable calcium sulphate beads in revision
arthroplasty for infection, Bone Joint J., 97-B, 1237–1241, https://doi.org/10.1302/0301-620X.97B9.34532, 2015.
Kallala, R., Harris, W. E., Ibrahim, M., Dipane, M., and McPherson, E.:
Use of Stimulan absorbable calcium sulphate beads in revision lower limb
arthroplasty: Safety profile and complication rates, Bone Joint Res., 7,
570–579, https://doi.org/10.1302/2046-3758.710.BJR-2017-0319.R1, 2018.
Kanellakopoulou, K., Panagopoulos, P., Giannitsioti, E., Tsaganos, T.,
Carrer, D.-P., Efstathopoulos, N., and Giamarellos-Bourboulis, E. J.: In
Vitro Elution of Daptomycin by a Synthetic Crystallic Semihydrate Form of
Calcium Sulfate, Stimulan, Antimicrob. Agents Chemother., 53, 3106–3107,
https://doi.org/10.1128/AAC.01490-08, 2009.
Kenna, D. M., Irojah, B. B., Mudge, K., and Eveler, K.: Absorbable
Antibiotic Beads Prophylaxis in Immediate Breast Reconstruction, Plast.
Reconstr. Surg., 141, 486e–492e, https://doi.org/10.1097/PRS.0000000000004203, 2018.
Kuo, T., Shaukat, R., and Giegerich, E.: Hypercalcemia from calcium
sulfate antibiotic beads: a lesson for endocrinologists, Endocr. Pract.,
25, 57–58, https://doi.org/10.1016/S1530-891X(20)46537-1, 2019.
Kurmis, A. P.: Eradicating Fungal Periprosthetic TKA “Super-infection”:
Review of the Contemporary Literature and Consideration of
Antibiotic-Impregnated Dissolving Calcium Sulfate Beads as a Novel PJI
Treatment Adjunct, Arthroplast. Today, 8, 163–170, https://doi.org/10.1016/j.artd.2021.02.009, 2021.
Kurtz, S., Ong, K., Lau, E., Mowat, F., and Halpern, M.: Projections of
primary and revision hip and knee arthroplasty in the United States from
2005 to 2030, J. Bone Joint Surg. Am., 89, 780–785, https://doi.org/10.2106/JBJS.F.00222, 2007.
Kurtz, S. M., Lau, E., Watson, H., Schmier, J. K., and Parvizi, J.:
Economic burden of periprosthetic joint infection in the United States, J.
Arthroplasty, 27, 61–65.e1, https://doi.org/10.1016/j.arth.2012.02.022, 2012.
Laycock, P. A., Cooper, J. J., Howlin, R. P., Delury, C., Aiken, S., and
Stoodley, P.: In Vitro Efficacy of Antibiotics Released from Calcium Sulfate
Bone Void Filler Beads, Materials, 11, 2265, https://doi.org/10.3390/ma11112265,
2018.
Liu, H. (Ed.): Nanocomposites for Musculoskeletal Tissue Regeneration, 1st edn.,
Elsevier, Philadelphia, PA, ISBN 978-1-78242-452-9, https://doi.org/10.1016/C2014-0-03007-9, 2016.
Luo, S., Jiang, T., Yang, Y., Yang, X., and Zhao, J.: Combination
therapy with vancomycin-loaded calcium sulfate and vancomycin-loaded PMMA in
the treatment of chronic osteomyelitis, BMC Musculoskelet. Disord., 17,
502, https://doi.org/10.1186/s12891-016-1352-9, 2016.
Maale, G. E., Eager, J. J., Mohammadi, D. K., and Calderon, F. A.:
Elution Profiles of Synthetic CaSO
4 Hemihydrate Beads Loaded with Vancomycin
and Tobramycin, Eur. J. Drug Metab. Pharmacokinet., 45, 547–555, https://doi.org/10.1007/s13318-020-00622-8, 2020a.
Maale, G. E., Eager, J. J., Srinivasaraghavan, A., Mohammadi, D. K., and
Kennard, N.: The evolution from the two stage to the one stage procedure for
biofilm based periprosthetic joint infections (PJI), Biofilm, 2, 100033,
https://doi.org/10.1016/j.bioflm.2020.100033, 2020b.
Malone, M., Goeres, D. M., Gosbell, I., Vickery, K., Jensen, S., and
Stoodley, P.: Approaches to biofilm-associated infections: the need for
standardized and relevant biofilm methods for clinical applications, Expert
Rev. Anti. Infect. Ther., 15, 147–156, https://doi.org/10.1080/14787210.2017.1262257, 2017.
McPherson, E. J., Dipane, M. V., and Sherif, S. M.: Dissolvable Antibiotic
Beads in Treatment of Periprosthetic Joint Infection and Revision
Arthroplasty – The Use of Synthetic Pure Calcium Sulfate
(Stimulan
®) Impregnated with Vancomycin & Tobramycin,
Reconstructive Review, 3, 32–43, https://doi.org/10.15438/rr.v3i1.27, 2013.
McPherson, E. J., Dipane, M. V., Chowdhry, M., and Wassef, A. J.: Fabrication of antibiotic-loaded dissolvable calcium sulfate beads: an in vitro mixing lab utilizing various antibiotic mixing formulas, J. Bone Joint Infect., 6, 405–412, https://doi.org/10.5194/jbji-6-405-2021, 2021.
Miclau, T., Dahners, L. E., and Lindsey, R. W.: In Vitro Pharmacokinetics
of Antibiotic Release from Locally Implantable Materials, J. Orthop. Res.,
11, 627–632, https://doi.org/10.1002/jor.1100110503, 1993.
Moore, K., Wilson-van Os, R., Dusane, D. H., Brooks, J. R., Delury, C.,
Aiken, S. S., Laycock, P. A., Sullivan, A. C., Granger, J. F., Dipane, M.
V., McPherson, E. J., and Stoodley, P.: Elution Kinetics from
Antibiotic-Loaded Calcium Sulfate Beads, Antibiotic-Loaded Polymethacrylate
Spacers, and a Powdered Antibiotic Bolus for Surgical Site Infections in a
Novel In Vitro Draining Knee Model, Antibiot. Basel Switz., 10, 270, https://doi.org/10.3390/antibiotics10030270, 2021.
Morley, R., Rothwell, M., Stephenson, J., McIlvenny, L., Webb, F., and
Barber, A.: Complex Foot Infection Treated With Surgical Debridement and
Antibiotic Loaded Calcium Sulfate – A Retrospective Cohort Study of 137
Cases, J. Foot Ankle Surg., 61, 239–247, https://doi.org/10.1053/j.jfas.2021.07.014,
2022.
Omar, M. A., Ahmed, H. A., Hammad, M. A., and Derayea, S. M.: Validated
spectrofluorimetric method for determination of selected aminoglycosides,
Spectrochim. Acta A. Mol. Biomol. Spectrosc., 135, 472–478, https://doi.org/10.1016/j.saa.2014.07.020, 2015.
Roberts, R., McConoughey, S. J., and Calhoun, J. H.: Size and composition
of synthetic calcium sulfate beads influence dissolution and elution rates
in vitro, J. Biomed. Mater. Res. Part B, 102B, 667–673, https://doi.org/10.1002/jbm.b.33045, 2014.
Santschi, E. M. and McGarvey, L.: In Vitro Elution of Gentamicin From
Plaster of Paris Beads, Vet. Surg., 32, 128–133, https://doi.org/10.1053/jvet.2003.50010, 2003.
Sindeldecker, D. and Stoodley, P.: The many antibiotic resistance and
tolerance strategies of
Pseudomonas aeruginosa, Biofilm, 3, 100056, https://doi.org/10.1016/j.bioflm.2021.100056, 2021.
Sindeldecker, D., Moore, K., Li, A., Wozniak, D. J., Anderson, M.,
Dusane, D. H., and Stoodley, P.: Novel Aminoglycoside-Tolerant Phoenix
Colony Variants of
Pseudomonas aeruginosa, Antimicrob. Agents Chemother.,
64, e00623-20, https://doi.org/10.1128/AAC.00623-20, 2020.
Trujillo, J. M., Logue, M. E., Kunkel, R., and Demas, C. P.: Off-label
Usage of Absorbable Beads Containing Antibiotics for Prevention of Surgical
Site Infections, Wounds, 29, E84–E87, https://doi.org/10.25270/wnds/2017.10.289296e84e87, 2017.
Wahl, P., Guidi, M., Benninger, E., Rönn, K., Gautier, E., Buclin,
T., Magnin, J.-L., and Livio, F.: The levels of vancomycin in the blood and
the wound after the local treatment of bone and soft-tissue infection with
antibiotic-loaded calcium sulfate as carrier material, Bone Joint J., 99-B,
1537–1544, https://doi.org/10.1302/0301-620X.99B11.BJJ-2016-0298.R3, 2017.
Wichelhaus, T. A., Dingeldein, E., Rauschmann, M., Kluge, S.,
Schäfer, V., and Brade, V.: Elution characteristics of vancomycin,
teicoplanin, gentamicin and clindamycin from calcium sulphate beads, J.
Antimicrob. Chemother., 48, 117–119, https://doi.org/10.1093/jac/48.1.117, 2001.
Zhang, H.-A., Zhou, C.-H., Meng, X.-Q., Fang, J., and Qin, C.-H.:
Intramedullary reaming and irrigation and antibiotic-loaded calcium sulfate
implantation for the treatment of infection after intramedullary nailing: a
retrospective study of 19 cases, BMC Musculoskelet. Disord., 21, 710,
https://doi.org/10.1186/s12891-020-03734-z, 2020.
