Journal of Bone and Joint Infection
Journal of Bone and Joint Infection
JBJI
Articles | Volume 6, issue 4
Articles | Volume 6, issue 4
https://doi.org/10.5194/jbji-6-73-2021
© Author(s) 2021. This work is distributed under
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/jbji-6-73-2021
© Author(s) 2021. This work is distributed under
the Creative Commons Attribution 4.0 License.
Articles | Volume 6, issue 4
Original full-length article
 | 
12 Jan 2021
Original full-length article |  | 12 Jan 2021

Bioactive glass S53P4 vs. autologous bone graft for filling defects in patients with chronic osteomyelitis and infected non-unions – a single center experience

Eva Steinhausen, Rolf Lefering, Martin Glombitza, Nikolaus Brinkmann, Carsten Vogel, Bastian Mester, and Marcel Dudda

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Latest update: 26 Oct 2025
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Short summary
We compared the outcome of bioactive glass S53P4 as bone substitute versus autologous bone grafts for filling defects in patients with infected non-union. Our comparison of the outcomes revealed no significant differences between the groups with respect to recurrence of infection, bone healing, full weight bearing, or complications in general. Our results are promising. BAG seems to be an appropriate bone substitute. Further studies with larger numbers of patients are required.
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