Articles | Volume 6, issue 9
J. Bone Joint Infect., 6, 457–466, 2021
https://doi.org/10.5194/jbji-6-457-2021
J. Bone Joint Infect., 6, 457–466, 2021
https://doi.org/10.5194/jbji-6-457-2021

Original full-length article 21 Dec 2021

Original full-length article | 21 Dec 2021

The effectiveness of antibiotic cement-coated nails in post-traumatic femoral and tibial osteomyelitis – comparative analysis of custom-made versus commercially available nails

Germán Garabano et al.

Cited articles

Barger, J., Fragomen, A. T., and Rozbruch, S. R.: Antibiotic-coated interlocking intramedullary nail for the treatment of long-bone osteomyelitis, J. Bone Joint Surg. Rev., 5, 1–10, https://doi.org/10.2106/JBJS.RVW.16.00095, 2017. 
Beals, R. K. and Bryant, R. E.: The treatment of chronic open osteomyelitis of the tibia in adults, Clin Orthop Relat Res., 433, 212–217, https://doi.org/10.1097/01.blo.0000150462.41498.fe, 2005. 
Bhadra, A. K. and Roberts, C. S.: Indications for antibiotic cement nails, J. Orthop. Trauma, 23, S26–30, https://doi.org/10.1097/BOT.0b013e31819f27aa, 2009. 
Blanchette, K. A. and Wenke, J. C.: Current therapies in treatment and prevention of fracture wound biofilms: why a multifaceted approach is essential for resolving persistent infections, J. Bone Joint Infect., 3, 50–67, https://doi.org/10.7150/jbji.23423, 2018. 
Centers for Disease Control and Prevention: CDC/NHSN Surveillance Definitions for Specific Types of Infections, available at: https://www.cdc.gov/nhsn/pdfs/pscmanual/17pscnosinfdef_current.pdf, last access: 9 December 2016. 
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Short summary
We present a series of patients with chronic post-traumatic osteomyelitis (CPTO) of the femur or tibia who were treated either with custom-made or commercially available antibiotic cement-coated nails. The overall infection control rate was 96.6 %, with reoperation and failure rates of 26.6 % and 3.3 %, respectively. Custom-made antibiotic-coated nails were associated with significantly longer operating times and higher rates of cement–nail debonding during removal.