Articles | Volume 6, issue 9
J. Bone Joint Infect., 6, 433–441, 2021
https://doi.org/10.5194/jbji-6-433-2021
J. Bone Joint Infect., 6, 433–441, 2021
https://doi.org/10.5194/jbji-6-433-2021
Original full-length article
01 Dec 2021
Original full-length article | 01 Dec 2021

Immunological evaluation of patients with orthopedic infections: taking the Cierny–Mader classification to the next level

Janet D. Conway et al.

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Short summary
Adding immunologic evaluation to the Cierny–Mader classification more accurately determines patients’ true host status and better quantifies risk and outcome with respect to orthopedic infection. Immunologically deficient A hosts should be quantified as B hosts. IgG deficiencies can be addressed with supplementation. IgG replacement should be considered in patients with recurrent orthopedic infections.