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Journal of Bone and Joint Infection An open-access journal of the European Bone and Joint Infection Society and the MusculoSkeletal Infection Society
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When we initiated this paper, there was no evidence on what kind of spacers we should use. Our work was to prove that we must use a broad spectrum of antibiotics at the spacers in two-stage revision procedures. We demonstrate that a large spectrum of antibiotics at the spacer results in a lower rate of positive cultures during preimplantation and, subsequently, better outcomes and lower rate of infection.
JBJI | Articles | Volume 6, issue 7
J. Bone Joint Infect., 6, 305–312, 2021
https://doi.org/10.5194/jbji-6-305-2021
J. Bone Joint Infect., 6, 305–312, 2021
https://doi.org/10.5194/jbji-6-305-2021

Original full-length article 10 Aug 2021

Original full-length article | 10 Aug 2021

Combined antibiotic therapy spacers either commercial or handmade are superior to monotherapy – a microbiological analysis at the second stage of revision

André Dias Carvalho et al.

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Short summary
When we initiated this paper, there was no evidence on what kind of spacers we should use. Our work was to prove that we must use a broad spectrum of antibiotics at the spacers in two-stage revision procedures. We demonstrate that a large spectrum of antibiotics at the spacer results in a lower rate of positive cultures during preimplantation and, subsequently, better outcomes and lower rate of infection.
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