Articles | Volume 6, issue 6
https://doi.org/10.5194/jbji-6-189-2021
© Author(s) 2021. This work is distributed under
the Creative Commons Attribution 4.0 License.
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/jbji-6-189-2021
© Author(s) 2021. This work is distributed under
the Creative Commons Attribution 4.0 License.
the Creative Commons Attribution 4.0 License.
Pursuit of the ideal antiseptic irrigation solution in the management of periprosthetic joint infections
Orthopaedic Institute of Central Jersey, a division of
Ortho Alliance NJ, 2315 Route 34 South
Manasquan, NJ 08736, USA
Hackensack Meridian School of Medicine, Department of Orthopedic Surgery, Hackensack, NJ, USA
Jersey Shore University Medical Center, Department of Orthopedic Surgery, Neptune, NJ, USA
Zuhdi E. Abdo
Rutgers New Jersey Medical School, Department of Orthopedics, Newark, NJ, 07103, USA
Bryan D. Springer
OrthoCarolina Hip and Knee Center, Department of Orthopedics Atrium Musculoskeletal Institute, Charlotte, NC, 28207, USA
Antonia F. Chen
Brigham & Women's Hospital, Department of Orthopedics, Boston, MA, 02115, USA
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Joseph J. Connolly, Marcos R. Gonzalez, Joshua B. Davis, Youssef H. Moussaoui, Graham S. Goh, Antonia F. Chen, Adam S. Olsen, and Santiago A. Lozano-Calderón
J. Bone Joint Infect., 10, 459–469, https://doi.org/10.5194/jbji-10-459-2025, https://doi.org/10.5194/jbji-10-459-2025, 2025
Short summary
Short summary
Periprosthetic joint infection (PJI) is a serious complication of oncologic joint reconstructions with large endoprosthetics. Although the microbiology of PJI in conventional joint replacements is well characterized, it is lacking for oncologic patients. This study found that the microbiology of oncologic PJI is distinct from conventional joint replacement PJI and that microbiology varies in different cancer subpopulations. These findings will help improve targeted antibiotic treatment for PJI.
Murillo Adrados, Michael M. Valenzuela, Bryan D. Springer, Susan M. Odum, Thomas K. Fehring, and Jesse E. Otero
J. Bone Joint Infect., 7, 51–53, https://doi.org/10.5194/jbji-7-51-2022, https://doi.org/10.5194/jbji-7-51-2022, 2022
Short summary
Short summary
Areas in orthopedics, such as spinal metastasis and sarcomas, have shown benefits of concentrated care in specialized centers. Currently in the US, no such centers exist for treatment of periprosthetic joint infection (PJI). We established a PJI center and review our first-year experience. Additionally, we note the complexity and volume of referrals, in addition to the abundant opportunities for research that referral centers provide. PJI centers are feasible and can improve PJI care.
Katherine Li, Mario Cuadra, Gregory Scarola, Susan Odum, Jesse Otero, William Griffin, and Bryan D. Springer
J. Bone Joint Infect., 6, 295–303, https://doi.org/10.5194/jbji-6-295-2021, https://doi.org/10.5194/jbji-6-295-2021, 2021
Short summary
Short summary
In total hip arthroplasty, infection remains one of the most devastating postoperative complications. It can be difficult to treat and eradicate. Currently there are several validated methods of combating infection but complications both during and after the process can derail the patient's recovery. We seek to determine complications that occur during the infection eradication process and the stage they occur in to bring awareness to possible reasons for failure of the revision.
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Short summary
Irrigation and debridement in the treatment of periprosthetic joint infection (PJI) serves an integral role in the eradication of bacterial burden and subsequent re-infection rates. Identifying the optimal irrigation agent, however, remains challenging, as there is limited data on superiority. Future clinical studies are needed to identify ideal irrigation solutions with optimal bactericidal properties and low cytotoxicity for PJI treatment.
Irrigation and debridement in the treatment of periprosthetic joint infection (PJI) serves an...