Articles | Volume 6, issue 6
https://doi.org/10.5194/jbji-6-189-2021
© Author(s) 2021. This work is distributed under
the Creative Commons Attribution 4.0 License.
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/jbji-6-189-2021
© Author(s) 2021. This work is distributed under
the Creative Commons Attribution 4.0 License.
the Creative Commons Attribution 4.0 License.
Pursuit of the ideal antiseptic irrigation solution in the management of periprosthetic joint infections
Orthopaedic Institute of Central Jersey, a division of
Ortho Alliance NJ, 2315 Route 34 South
Manasquan, NJ 08736, USA
Hackensack Meridian School of Medicine, Department of Orthopedic Surgery, Hackensack, NJ, USA
Jersey Shore University Medical Center, Department of Orthopedic Surgery, Neptune, NJ, USA
Zuhdi E. Abdo
Rutgers New Jersey Medical School, Department of Orthopedics, Newark, NJ, 07103, USA
Bryan D. Springer
OrthoCarolina Hip and Knee Center, Department of Orthopedics Atrium Musculoskeletal Institute, Charlotte, NC, 28207, USA
Antonia F. Chen
Brigham & Women's Hospital, Department of Orthopedics, Boston, MA, 02115, USA
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42 citations as recorded by crossref.
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- Polymicrobial infection requires higher concentration of irrigation solution than monomicrobial infection to eradicate biofilm grown on titanium surface: an in-vitro analysis D. Semeshchenko et al. https://doi.org/10.1016/j.jhin.2026.06.026
- Immediate salvage procedure for infected penile prostheses: A review of the advances in surgical technique and antimicrobial strategies M. Mahdi et al. https://doi.org/10.1038/s41443-025-01133-3
- Chlorhexidine or Povidone-Iodine Solution Irrigation Versus Saline Irrigation for the Prevention of Postoperative Infections in Primary Total Joint Arthroplasty: A Systematic Review and Meta-Analysis E. Machinski et al. https://doi.org/10.1016/j.arth.2025.02.037
- Comparing the in Vitro Efficacy of Commonly Used Surgical Irrigants for the Treatment of Implant-Associated Infections C. Hamad et al. https://doi.org/10.2106/JBJS.24.01225
- Infection of the artificial urinary sphincter: Prevention, diagnosis, and management J. Loh-Doyle et al. https://doi.org/10.4103/ijru.ijru_17_24
- BENEFICIAL EFFECTS OF A NOVEL INTRAOPERATIVE SURGICAL IRRIGANT ON POST-OPERATIVE KNEE SWELLING AND LIMB FUNCTION IN PRIMARY TOTAL KNEE ARTHROPLASTY L. Battista & A. Wickline https://doi.org/10.60118/001c.89994
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- An In Vitro Study to Assess the Best Strategy for the Chemical Debridement of Periprosthetic Joint Infection M. Márquez-Gómez et al. https://doi.org/10.3390/antibiotics12101507
- Does a Specific Sequential Combination of Antiseptic Solutions for Chemical Debridement in Periprosthetic Joint Infection Improve Outcomes vs. Solution Alone? An In Vivo Study M. Márquez-Gómez et al. https://doi.org/10.3390/antibiotics13121225
- Antiseptic Irrigation Solutions Used in Total Joint Arthroplasty Z. Christopher et al. https://doi.org/10.2106/JBJS.RVW.21.00225
- The In Vitro Performance of Surgical Irrigation Solutions in Preventing Biofilm Formation on Implants F. Tabatabaei et al. https://doi.org/10.1016/j.arth.2025.11.026
- Optimal protocol for intraoperative irrigation to prevent periprosthetic joint infection T. Kataoka et al. https://doi.org/10.1302/2046-3758.151.BJR-2025-0122.R1
Latest update: 07 Sep 2026
Short summary
Irrigation and debridement in the treatment of periprosthetic joint infection (PJI) serves an integral role in the eradication of bacterial burden and subsequent re-infection rates. Identifying the optimal irrigation agent, however, remains challenging, as there is limited data on superiority. Future clinical studies are needed to identify ideal irrigation solutions with optimal bactericidal properties and low cytotoxicity for PJI treatment.
Irrigation and debridement in the treatment of periprosthetic joint infection (PJI) serves an...