Journal of Bone and Joint Infection
Journal of Bone and Joint Infection
JBJI
Articles | Volume 6, issue 5
Articles | Volume 6, issue 5
https://doi.org/10.5194/jbji-6-147-2021
© Author(s) 2021. This work is distributed under
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/jbji-6-147-2021
© Author(s) 2021. This work is distributed under
the Creative Commons Attribution 4.0 License.
Articles | Volume 6, issue 5
Brief report
 | 
26 Apr 2021
Brief report |  | 26 Apr 2021

Safety and tolerability of liquid amikacin in antibiotic-loaded bone cement – a case series

Don Bambino Geno Tai, Nathan J. Brinkman, Omar Abu Saleh, Douglas R. Osmon, Matthew P. Abdel, and Christina G. Rivera

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Latest update: 28 Apr 2026
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Short summary
Antibiotics are frequently used in bone cement during joint replacements or treatment of bone and joint infections. Amikacin is rarely used in bone cement, particularly the liquid formulation. We describe a series of patients in which liquid amikacin was incorporated into bone cement. We did not observe the occurrence of adverse drug reactions definitively attributed to its use. All patients had favorable outcomes.
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