Journal of Bone and Joint Infection
Journal of Bone and Joint Infection
JBJI
Articles | Volume 11, issue 1
Articles | Volume 11, issue 1
https://doi.org/10.5194/jbji-11-83-2026
© Author(s) 2026. This work is distributed under
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/jbji-11-83-2026
© Author(s) 2026. This work is distributed under
the Creative Commons Attribution 4.0 License.
Articles | Volume 11, issue 1
Original full-length article
 | 
10 Feb 2026
Original full-length article |  | 10 Feb 2026

High failure rate in Pseudomonas aeruginosa-associated periprosthetic hip and knee joint infections

Ece Akcicek, Jennyfer A. Mitterer, Veronika Achatz, Tamino Szirmay, Sujeesh Sebastian, and Jochen G. Hofstaetter

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Short summary
Pseudomonas aeruginosa is a common pathogen in Gram-negative periprosthetic joint infections (PJIs). It is resistant to many antibiotics and forms biofilm, making it difficult to treat. We analyzed 1286 patients who underwent 1640 surgeries; among them, 38 patients with 50 procedures had P. aeruginosa. Most infections were chronic, often in hip revisions, with a high failure rate and recurrence. Due to its clinical and microbiological features, P. aeruginosa-related PJIs remain challenging.

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