Articles | Volume 11, issue 4
https://doi.org/10.5194/jbji-11-463-2026
https://doi.org/10.5194/jbji-11-463-2026
Original full-length article
 | 
03 Aug 2026
Original full-length article |  | 03 Aug 2026

Timing from admission to debridement, antibiotic, and implant retention (DAIR) affects mortality risk in total hip prosthetic joint infections

Jack Legler, Samuel Morgan, Paul Beaulé, Hesham Abdelbary, George Grammatopoulos, and Simon Garceau

Cited articles

Bourget-Murray, J., Azad, M., Gofton, W., Abdelbary, H., Garceau, S., and Grammatopoulos, G.: Is the routine use of local antibiotics in the management of periprosthetic joint infections justified?, Hip Int., 33, 4–16, https://doi.org/10.1177/11207000221139467, 2023. 
Bourget-Murray, J., Tubin, N., Bureau, A., Morris, J., Ann Azad, M., Abdelbary, H., Grammatopoulos, G., and Garceau, S.: Lower Rates of Reoperation Following Partial or Complete Revision Arthroplasty Compared to Debridement, Antibiotics, and Implant Retention for Early Postoperative and Acute Hematogenous Periprosthetic Hip Infection, J. Arthroplasty, 39, 2346–2351, https://doi.org/10.1016/j.arth.2024.03.054, 2024. 
Chotanaphuti, T., Courtney, P. M., Fram, B., In den Kleef, N. J., Kim, T. K., Kuo, F. C., Lustig, S., Moojen, D. J., Nijhof, M., Oliashirazi, A., Poolman, R., Purtill, J. J., Rapisarda, A., Rivero-Boschert, S., and Veltman, E. S.: Hip and Knee Section, Treatment, Algorithm: Proceedings of International Consensus on Orthopedic Infections, J. Arthroplasty, 34, S393–S397, https://doi.org/10.1016/j.arth.2018.09.024, 2019. 
Coughlan, A. and Taylor, F.: Classifications in Brief: The McPherson Classification of Periprosthetic Infection, Clin. Orthop. Relat. R., 478, 903–908, https://doi.org/10.1097/CORR.0000000000001133, 2020. 
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Short summary
We studied patients with infected hip replacements to determine whether delays between hospital admission and  surgery affected recovery. By reviewing patient records from a specialty center, we found that longer delays were linked to a higher risk of death within 90 d. Older age, poorer overall health, and low blood levels also increased the chance of complications or repeat surgery. These results suggest that prompt treatment and careful health preparation can improve outcomes. 
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