Articles | Volume 11, issue 1
https://doi.org/10.5194/jbji-11-1-2026
© Author(s) 2026. This work is distributed under the Creative Commons Attribution 4.0 License.
Synovial fluid α-defensin might be false positive in early stages after major total arthroplasty revision surgery
Related authors
Cited articles
Bingham, J., Clarke, H., Spangehl, M., Schwartz, A., Beauchamp, C., and Goldberg, B.: The Alpha Defensin-1 Biomarker Assay can be Used to Evaluate the Potentially Infected Total Joint Arthroplasty, Clinical Orthopaedics and Related Research®, 472, 4006–4009, https://doi.org/10.1007/s11999-014-3900-7, 2014.
Cooper, K. B., Siegel, E. R., Stambough, J. B., Bumpass, D. B., and Mears, S. C.: The Alpha-Defensin Prosthetic Joint Infection Test Has Poor Validity for Native Knee Joint Infection, J. Arthroplasty, 36, 2957–2961, https://doi.org/10.1016/j.arth.2021.03.020, 2021.
Davis, C.: Generalizing from clinical trials, Controlled Clinical Trials 15, 11–14, https://doi.org/10.1016/0197-2456(94)90023-x, 1994.
Heckmann, N. D., Wang, J. C., Liu, K. C., Won, P., Chung, B. C., Mayer, L. W., Longjohn, D. B., Oakes, D. A., Christ, A. B., and Lieberman, J. R.: Refining the Role of Routine Synovial Alpha-Defensin in Periprosthetic Joint Infection Following Total Knee Arthroplasty: An Analysis of Limitations, Journal of Arthroplasty, 38, 2691–2697, https://doi.org/10.1016/j.arth.2023.05.095, 2023.
Kim, S.-J. and Cho, Y. J.: Current Guideline for Diagnosis of Periprosthetic Joint Infection: A Review Article, Hip and Pelvis, 33, 11–17, https://doi.org/10.5371/hp.2021.33.1.11, 2021.