Articles | Volume 10, issue 2
https://doi.org/10.5194/jbji-10-85-2025
https://doi.org/10.5194/jbji-10-85-2025
Review
 | 
28 Mar 2025
Review |  | 28 Mar 2025

The hidden connection between gut microbiota and periprosthetic joint infections: a scoping review

Alessandro Singlitico, Daniele Grassa, Rami Kaplan, Alessandro Smimmo, Giulio Maccauro, and Raffaele Vitiello

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Short summary
In this article we discuss how gut microbiota can affect the outcomes of a total joint arthroplasty. Total joint arthroplasty is a safe procedure for improving the quality of life in patients affected by arthrosis. Periprosthetic joint infection (PJI) is relatively rare but represents one of the most common causes of implant failure requiring revision surgery. Recently, there has been a major interest in the role of gut microbiome, in particular dysbiosis, as a risk factor for PJI.
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