Journal of Bone and Joint Infection
Journal of Bone and Joint Infection
JBJI
Articles | Volume 10, issue 6
Articles | Volume 10, issue 6
https://doi.org/10.5194/jbji-10-543-2025
© Author(s) 2025. This work is distributed under
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/jbji-10-543-2025
© Author(s) 2025. This work is distributed under
the Creative Commons Attribution 4.0 License.
Articles | Volume 10, issue 6
Original full-length article
 | 
05 Dec 2025
Original full-length article |  | 05 Dec 2025

Cause of death following revision for periprosthetic joint infection or major aseptic revision in total hip and knee arthroplasty

Nicolai Kjældgaard Kristensen, Per Hviid Gundtoft, Brian Elmengaard, Alma Becic Pedersen, and Jeppe Lange

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Short summary
Patients who undergo repeat surgery due to joint infection after a hip or knee replacement have a higher risk of dying compared with those who have revision surgery for other reasons. We studied more than 9000 patients using national health data to explore why this happens. We found that the higher risk cannot be explained by a single cause of death but is linked to many common health problems. This suggests that these patients are especially vulnerable and may need broader medical support.
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