Journal of Bone and Joint Infection
Journal of Bone and Joint Infection
JBJI
Articles | Volume 10, issue 6
Articles | Volume 10, issue 6
https://doi.org/10.5194/jbji-10-459-2025
© Author(s) 2025. This work is distributed under
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/jbji-10-459-2025
© Author(s) 2025. This work is distributed under
the Creative Commons Attribution 4.0 License.
Articles | Volume 10, issue 6
Original full-length article
 | 
18 Nov 2025
Original full-length article |  | 18 Nov 2025

Microbiological profile of prosthetic joint infections in orthopedic oncology: a comparison with conventional joint arthroplasty

Joseph J. Connolly, Marcos R. Gonzalez, Joshua B. Davis, Youssef H. Moussaoui, Graham S. Goh, Antonia F. Chen, Adam S. Olsen, and Santiago A. Lozano-Calderón

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Short summary
Periprosthetic joint infection  (PJI) is a serious complication of oncologic joint reconstructions with large endoprosthetics. Although the microbiology of PJI in conventional joint replacements is well characterized, it is lacking for oncologic patients. This study found that the microbiology of oncologic PJI is distinct from conventional joint replacement PJI and that microbiology varies in different cancer subpopulations. These findings will help improve targeted antibiotic treatment for PJI.
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