Articles | Volume 10, issue 4
https://doi.org/10.5194/jbji-10-265-2025
https://doi.org/10.5194/jbji-10-265-2025
Original full-length article
 | 
11 Aug 2025
Original full-length article |  | 11 Aug 2025

Proteus-species-associated periprosthetic hip and knee joint infections – a 15-year cohort analysis

Veronika Achatz, Jennyfer A. Mitterer, Stephanie Huber, Ece Akcicek, Selma Tobudic, Sujeesh Sebastian, and Jochen G. Hofstaetter

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Cited articles

Aboltins, C. A., Dowsey, M. M., Buising, K. L., Peel, T. N., Daffy, J. R., Choong, P. F. M., and Stanley, P. A.: Gram-negative prosthetic joint infection treated with debridement, prosthesis retention and antibiotic regimens including a fluoroquinolone, Clin. Microbiol. Infec., 17, 862–867, https://doi.org/10.1111/j.1469-0691.2010.03361.x, 2011. 
Armbruster, C. E., Mobley, H. L. T., and Pearson, M. M.: Pathogenesis of Proteus mirabilis Infection, EcoSal Plus, 8, https://doi.org/10.1128/ecosalplus.ESP-0009-2017, 2018. 
Blanchard, N. P., Browne, J. A., and Werner, B. C.: The Timing of Preoperative Urinary Tract Infection Influences the Risk of Prosthetic Joint Infection Following Primary Total Hip and Knee Arthroplasty, J. Arthroplasty, 37, 2251–2256, https://doi.org/10.1016/j.arth.2022.05.034, 2022. 
Charlson, M. E., Pompei, P., Ales, K. L., and MacKenzie, C. R.: A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation, J. Chron. Dis., 40, 373–383, https://doi.org/10.1016/0021-9681(87)90171-8, 1987. 
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Short summary
Proteus is a rare form of bacteria in periprosthetic joint infection (PJI) following knee and hip arthroplasties. In this study, we investigated culture-positive revision surgeries from 2008 until 2024. Proteus species were mainly found in hip arthroplasties. Furthermore, the infections of Proteus species were mainly prevalent in chronic revisions alongside multiple bacteria. Given their chronic and polymicrobial nature, the outcome of Proteus-associated PJIs is poor. 
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