Journal of Bone and Joint Infection
Journal of Bone and Joint Infection
JBJI
Articles | Volume 10, issue 4
Articles | Volume 10, issue 4
https://doi.org/10.5194/jbji-10-225-2025
© Author(s) 2025. This work is distributed under
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/jbji-10-225-2025
© Author(s) 2025. This work is distributed under
the Creative Commons Attribution 4.0 License.
Articles | Volume 10, issue 4
Original full-length article
 | 
23 Jul 2025
Original full-length article |  | 23 Jul 2025

Type of acute periprosthetic joint infection may not affect failure of debridement, antibiotics, and implant retention after total knee arthroplasty

Andrew J. Frear, Michael F. Shannon, Shaan Sadhwani, Anthony O. Kamson, Clair Smith, Charity G. Patterson, Victoria R. Wong, Frank Johannes Plate, and Kenneth L. Urish

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No difference in failure between static, articulating, and prosthetic low-friction spacers for periprosthetic joint infection of total knee arthroplasty
Michael F. Shannon, Timothy Edwards, Timothy Maurer, Andrew J. Frear, Victoria R. Wong, Shaan Sadhwani, Clair Smith, Anthony Kamson, Brian Omslaer, Christian Cisneros, Andrew Gordon, Akeem Williams, Neel B. Shah, and Kenneth L. Urish
J. Bone Joint Infect., 10, 243–253, https://doi.org/10.5194/jbji-10-243-2025,https://doi.org/10.5194/jbji-10-243-2025, 2025
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Cited articles

Aboltins, C. A., Dowsey, M. M., Buising, K. L., Peel, T. N., Daffy, J. R., Choong, P. F., and Stanley, P. A.: Gram-negative prosthetic joint infection treated with debridement, prosthesis retention and antibiotic regimens including a fluoroquinolone, Clin. Microbiol. Infec., 17, 862–867, https://doi.org/10.1111/j.1469-0691.2010.03361.x, 2011. 
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Balato, G., Ascione, T., de Matteo, V., Lenzi, M., Amato, M., de Giovanni, R., Festa, E., and Mariconda, M.: Debridement and implant retention in acute hematogenous periprosthetic joint infection after knee arthroplasty: a systematic review, Orthop. Rev. (Pavia), 14, 33670, https://doi.org/10.52965/001c.33670, 2022. 
Bernaus, M., Aunon-Rubio, A., Monfort-Mira, M., Arteagoitia-Colino, I., Martinez-Ros, J., Castellanos, J., Lamo-Espinosa, J. M., Arguelles, F., Veloso, M., Gomez Garcia, L., Crespo, F. A., Sanchez-Fernandez, J., Murias-Alvarez, J., Marti-Garin, D., Hernandez-Gonzalez, N., Villarejo-Fernandez, B., Valero-Cifuentes, G., Hernandez-Torres, A., Molina-Gonzalez, J., Coifman-Lucena, I., Esteban-Moreno, J., Demaria, P., Esteve-Palau, E., Del Pozo, J. L., Suarez, A., Carmona-Torre, F., Daras, A., Baeza, J., and Font-Vizcarra, L.: Risk Factors of DAIR Failure and Validation of the KLIC Score: A Multicenter Study of Four Hundred Fifty-Five Patients, Surg. Infect. (Larchmt), 23, 280–287, https://doi.org/10.1089/sur.2021.320, 2022. 
Bozic, K. J., Kurtz, S. M., Lau, E., Ong, K., Chiu, V., Vail, T. P., Rubash, H. E., and Berry, D. J.: The epidemiology of revision total knee arthroplasty in the United States, Clin. Orthop. Relat. R., 468, 45–51, https://doi.org/10.1007/s11999-009-0945-0, 2010. 
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Short summary
This retrospective study compared debridement and implant retention failure for three types of acute knee replacement infection and analyzed outcomes for patients in a cohort with low medical risk. No differences in failure rate were seen between types in the overall sample or “optimal” cohort. Staphylococcus aureus was less common in later infection, while Streptococcus was less frequent in earlier infection. In an optimal patient, similar outcomes between types may suggest that medical factors do not alter risk.
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