Articles | Volume 10, issue 4
https://doi.org/10.5194/jbji-10-225-2025
https://doi.org/10.5194/jbji-10-225-2025
Original full-length article
 | 
23 Jul 2025
Original full-length article |  | 23 Jul 2025

Type of acute periprosthetic joint infection may not affect failure of debridement, antibiotics, and implant retention after total knee arthroplasty

Andrew J. Frear, Michael F. Shannon, Shaan Sadhwani, Anthony O. Kamson, Clair Smith, Charity G. Patterson, Victoria R. Wong, Frank Johannes Plate, and Kenneth L. Urish

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Cited articles

Aboltins, C. A., Dowsey, M. M., Buising, K. L., Peel, T. N., Daffy, J. R., Choong, P. F., and Stanley, P. A.: Gram-negative prosthetic joint infection treated with debridement, prosthesis retention and antibiotic regimens including a fluoroquinolone, Clin. Microbiol. Infec., 17, 862–867, https://doi.org/10.1111/j.1469-0691.2010.03361.x, 2011. 
Anderson, D. J. and Kaye, K. S.: Staphylococcal surgical site infections, Infect. Dis. Clin. North Am., 23, 53–72, https://doi.org/10.1016/j.idc.2008.10.004, 2009. 
Balato, G., Ascione, T., de Matteo, V., Lenzi, M., Amato, M., de Giovanni, R., Festa, E., and Mariconda, M.: Debridement and implant retention in acute hematogenous periprosthetic joint infection after knee arthroplasty: a systematic review, Orthop. Rev. (Pavia), 14, 33670, https://doi.org/10.52965/001c.33670, 2022. 
Bozic, K. J., Kurtz, S. M., Lau, E., Ong, K., Chiu, V., Vail, T. P., Rubash, H. E., and Berry, D. J.: The epidemiology of revision total knee arthroplasty in the United States, Clin. Orthop. Relat. R., 468, 45–51, https://doi.org/10.1007/s11999-009-0945-0, 2010. 
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Short summary
This retrospective study compared debridement and implant retention failure for three types of acute knee replacement infection and analyzed outcomes for patients in a cohort with low medical risk. No differences in failure rate were seen between types in the overall sample or “optimal” cohort. Staphylococcus aureus was less common in later infection, while Streptococcus was less frequent in earlier infection. In an optimal patient, similar outcomes between types may suggest that medical factors do not alter risk.
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