This retrospective study shows that autogenous non-vascularized bone graft is a viable option for managing post-osteomyelitis bone defects in children in low-resource settings. Bone union was achieved in all cases at the last follow-up (minimum of 7 years). Recurrence of infection was seen in two cases. Studies into this specific technique are important as it does not require super-specialized centres or skills, both of which are scarce in low-resource settings.

Bone infection (osteomyelitis) due to Mycobacterium fortuitum, a human pathogen commonly found in soil and water, is a rare disease. Treatment includes antibiotics and surgical removal of infected bone, leaving a bony defect that must be repaired to prevent reinfection and the risk of fracture. Here, M. fortuitum osteomyelitis of the cuboid bone was treated with synthetic antibiotic-loaded cement, successfully resolving inflammation and bone defect filling as well as promoting bone regeneration.

The use of dissolving local antibiotic delivery systems in orthopedic surgery is improving the way we treat infection. Early analysis of a small cohort suggests that antibiotic-loaded calcium sulfate-coated interlocking intramedullary nails (CS-IMN) are safe and may be as effective as the more established method for infection eradication. Future studies with larger cohorts of patients will be required to confirm these findings.

This study consists of 26 patients with infection of the pubic symphysis. The authors believe that by drawing awareness to this condition patients may be diagnosed and undergo surgery faster; 21 of the patients had pelvic surgery before onset of pubic infection. The diagnostic delay was between 1 and 12 months. All patients underwent surgical debridement and received a minimum of 6 weeks antibiotic treatment; 23 patients had postoperative pain relief and 19 patients were ambulant without aids.

Osteomyelitis is an infection of bone and is often treated with surgical debridement. This results in a bone defect which requires the use of a void filler. This study evaluated the use of a gentamicin-impregnated ceramic void filler (CERAMENT G) and compared it to the same void filler without antibiotic (CERAMENT) and no void filler in a rat model of osteomyelitis. CERAMENT G was found to decrease the rate of persistent infection and grow more new bone than CERAMENT or an empty defect.