Journal of Bone and Joint Infection
Journal of Bone and Joint Infection
JBJI
Articles | Volume 10, issue 2
Articles | Volume 10, issue 2
https://doi.org/10.5194/jbji-10-143-2025
© Author(s) 2025. This work is distributed under
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/jbji-10-143-2025
© Author(s) 2025. This work is distributed under
the Creative Commons Attribution 4.0 License.
Articles | Volume 10, issue 2
Review
 | 
08 Apr 2025
Review |  | 08 Apr 2025

Oral tetracyclines for bone and joint infections: what do we know?

Tom Cartau, Jocelyn Michon, Renaud Verdon, and Aurelie Baldolli

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Short summary
Bone and joint infections are common and generally require surgical treatment combined with prolonged antibiotic therapy. It is important to use an antibiotic with good bone penetration that is effective against the commonly encountered pathogens and well-tolerated. Oral tetracyclines are promising and frequently used candidates. This review summarizes the available data on the use of oral tetracyclines in bone and joint infections and highlights the limited data available.
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