90 citations as recorded by crossref.

1. Managing Bone Infections Beyond Systemic Antibiotics: A Scoping Review E. Polyzou et al. https://doi.org/10.3390/pathogens15020201
2. Comparative effectiveness of antimicrobial implant surface coatings in preventing orthopaedic implant-associated infections: a network meta-analysis R. Elsheikh et al. https://doi.org/10.1007/s00402-026-06225-3
3. Economic Evaluation of Antibacterial Coatings on Healthcare Costs in First Year Following Total Joint Arthroplasty M. Trentinaglia et al. https://doi.org/10.1016/j.arth.2018.01.057
4. Phenotypic Modulation of Biofilm Formation in a Staphylococcus epidermidis Orthopedic Clinical Isolate Grown Under Different Mechanical Stimuli: Contribution From a Combined Proteomic Study M. Bottagisio et al. https://doi.org/10.3389/fmicb.2020.565914
5. Needle-injectable microcomposite cryogel scaffolds with antimicrobial properties K. Joshi Navare et al. https://doi.org/10.1038/s41598-020-75196-1
6. The Efficacy of Defensive Antibacterial Coating (DAC™) Periprosthetic Joint Infection Prevention in the Hip: A Systematic Review A. Bove et al. https://doi.org/10.3390/jcm14010270
7. Implant surface modifications as a prevention method for periprosthetic joint infection caused by Staphylococcus aureus: a systematic review and meta-analysis K. Phatama et al. https://doi.org/10.5194/jbji-7-231-2022
8. Bioabsorbable Hydrogel Coating for Infection Prevention in Fracture Fixation: A Retrospective Matched Case–Control Study C. Ciccullo et al. https://doi.org/10.3390/ph19030518
9. Local Antibiotic Delivery Options in Prosthetic Joint Infection W. Steadman et al. https://doi.org/10.3390/antibiotics12040752
10. Bioactive Hydroxyapatite-Magnesium Phosphate Coatings Deposited by MAPLE for Preventing Infection and Promoting Orthopedic Implants Osteointegration D. Florea et al. https://doi.org/10.3390/ma15207337
11. Reconstruction of infected post-traumatic bone defects of the distal femur with the CompressⓇ implant. Preliminary results of a staged non-biological strategy P. Corona et al. https://doi.org/10.1016/j.injury.2020.10.016
12. Antimicrobial coatings for orthopaedic implants - Ready for use? V. Alt & A. Chen https://doi.org/10.7150/jbji.46508
13. Defensive antibacterial coating in orthopaedic surgery: Current evidence and future direction R. Roberts et al. https://doi.org/10.5312/wjo.v16.i7.107575
14. The road after cancer: biomaterials and tissue engineering approaches to mediate the tumor microenvironment post-cancer treatment L. Westwood et al. https://doi.org/10.3389/fbiom.2024.1347324
15. Effects of antibiotics encapsulated in hyaluronic acid hydrogels on different osteogenic cells and bacteria D. Argyrakis et al. https://doi.org/10.1007/s00441-026-04053-w
16. Intraoperative loading of calcium phosphate-coated implants with gentamicin prevents experimental Staphylococcus aureus infection in vivo K. Thompson et al. https://doi.org/10.1371/journal.pone.0210402
17. Current Concepts of Local Antibiotic Delivery in Bone and Joint Infections—A Narrative Review of Techniques and Clinical Experiences C. Berberich https://doi.org/10.3390/microorganisms13102276
18. Systemic and local antimicrobial strategies to prevent Periprosthetic joint infection S. Yoon et al. https://doi.org/10.1080/14787210.2025.2586067
19. Making waves: how ultrasound-targeted drug delivery is changing pharmaceutical approaches L. Delaney et al. https://doi.org/10.1039/D1MA01197A
20. Antibiotic-Loaded Hydrogel for the Treatment of Lower-Limb Fracture-Related Infections: A Single Center’s Multidisciplinary Experience D. De Meo et al. https://doi.org/10.3390/gels10100628
21. DAC®, a Hyaluronan Derivative in the Form of a Gel, Is Effective in Preventing Periprosthetic Joint Infection During Arthroplasty Revision in Patients with Comorbidities: A Retrospective, Observational, 1:1-Matched Case–Control Clinical Investigation G. Ricciardi et al. https://doi.org/10.3390/biomedicines13102408
22. Is coating of titanium implants effective at preventing Staphylococcus aureus infections? A meta-analysis of animal model studies K. Tsikopoulos et al. https://doi.org/10.1007/s00264-020-04660-4
23. Efficacy and safety of intrawound vancomycin in primary hip and knee arthroplasty H. Xu et al. https://doi.org/10.1302/2046-3758.911.BJR-2020-0190.R2
24. Computer-aided hydrogel synthesis for 3D bioprinting: application of design of experiments (DoE), machine learning (ML), and computational fluid dynamics (CFD) M. Nguyen et al. https://doi.org/10.1039/D6MA00268D
25. Prevalence and burden of orthopaedic implantable-device infections in Italy: a hospital-based national study L. Pirisi et al. https://doi.org/10.1186/s12879-020-05065-9
26. 2025 ICM: Sutures and Dressings R. Sharma et al. https://doi.org/10.1016/j.arth.2025.10.086
27. Toward Designing of Anti-infective Hydrogels for Orthopedic Implants: From Lab to Clinic D. Garg et al. https://doi.org/10.1021/acsbiomaterials.0c01408
28. Fast-resorbable antibiotic-loaded hydrogel coating to reduce post-surgical infection after internal osteosynthesis: a multicenter randomized controlled trial K. Malizos et al. https://doi.org/10.1007/s10195-017-0442-2
29. Is Implant Coating With Tyrosol- and Antibiotic-loaded Hydrogel Effective in Reducing Cutibacterium (Propionibacterium) acnes Biofilm Formation? A Preliminary In Vitro Study K. Tsikopoulos et al. https://doi.org/10.1097/CORR.0000000000000663
30. Systematic Review of Antimicrobial Biomaterials for Medical Implants: Clinical Strategies for Reducing Device-Associated Infections A. Olowookere et al. https://doi.org/10.63946/jebm/18874
31. Dual antibiotic loaded bone cement in patients at high infection risks in arthroplasty: Rationale of use for prophylaxis and scientific evidence C. Berberich et al. https://doi.org/10.5312/wjo.v12.i3.119
32. Clinical Application of Antibacterial Hydrogel and Coating in Orthopaedic and Traumatology Surgery D. De Meo et al. https://doi.org/10.3390/gels7030126
33. Two-stage cementless hip revision for peri-prosthetic infection with an antibacterial hydrogel coating: results of a comparative series L. Zagra et al. https://doi.org/10.1007/s00264-018-4206-2
34. Drug-Releasing Tannic Acid-Mediated Adhesive PEG Hydrogel for Porous Titanium Implants T. Bubpamala et al. https://doi.org/10.1021/acsomega.3c06966
35. Local Antibacterial Implant Protection in Orthopedics and Trauma: What’s New? C. Romanò et al. https://doi.org/10.21823/2311-2905-2019-25-4-64-74
36. What to Know about Antimicrobial Coatings in Arthroplasty: A Narrative Review F. Onorato et al. https://doi.org/10.3390/medicina60040574
37. Periprosthetic joint infection after arthroplasty: advances and future prospects X. Xiong et al. https://doi.org/10.1186/s13018-025-06257-2
38. Efficacy of antimicrobial coated orthopaedic implants on the prevention of periprosthetic infections: a systematic review and meta-analysis O. Savvidou et al. https://doi.org/10.7150/jbji.44839
39. Pharmacotherapy options and drug development in managing periprosthetic joint infections in the elderly A. Macias-Valcayo et al. https://doi.org/10.1080/14656566.2019.1602118
40. Natural-Based Hydrogels for Bone Regeneration: Emerging Technologies and Translational Perspectives H. Anees et al. https://doi.org/10.3390/jfb17100498
41. Antibiotic-Loaded Hydrogel Coating to Reduce Early Postsurgical Infections in Aseptic Hip Revision Surgery: A Retrospective, Matched Case-Control Study D. De Meo et al. https://doi.org/10.3390/microorganisms8040571
42. Progress in Designing Therapeutic Antimicrobial Hydrogels Targeting Implant‐associated Infections: Paving the Way for a Sustainable Platform Applied to Biomedical Devices C. Dini et al. https://doi.org/10.1002/adhm.202402926
43. Emerging materials and technologies for advancing bioresorbable surgical meshes B. Shiroud Heidari et al. https://doi.org/10.1016/j.actbio.2024.06.012
44. A retrospective study of antibacterial iodine-coated implants for postoperative infection T. Shirai et al. https://doi.org/10.1097/MD.0000000000017932
45. Translation and validation of the Greek version of the “ASEPSIS” scoring method for orthopaedic wound infections P. Copanitsanou et al. https://doi.org/10.1016/j.ijotn.2018.11.006
46. Early Experience With Defensive Antibacterial Coating (DAC®) Hydrogel in High-Risk Orthopaedic Implant Surgery S. Sasi Kumar Menon et al. https://doi.org/10.7759/cureus.114499
47. DOES TOPICAL USE OF GENTAMICIN REDUCE THE INFECTION RATE IN PRIMARY TOTAL HIP ARTHROPLASTY? C. Oliveira et al. https://doi.org/10.1590/1413-785220192704219177
48. Defensive antibacterial coating (DAC) hydrogel with gentamycin and vancomycin for the therapy of achilles tendon infection after surgical repair without massive soft-tissue defect. Results in 8 cases I. Babiak et al. https://doi.org/10.2478/ahem-2023-0022
49. Hyaluronic acid-g-poly(lactic acid) and poly(vinyl alcohol) inks for 3D printed berberine loaded foldable dressings N. Virzì et al. https://doi.org/10.1016/j.apmt.2025.102978
50. Single-stage transcutaneous osseointegrated prosthesis for above-knee amputations including an antibiotic-loaded hydrogel. Preliminary results of a new surgical protocol P. Corona et al. https://doi.org/10.1016/j.injury.2024.111424
51. The Intraoperative Use of Defensive Antibacterial Coating (DAC®) in the Form of a Gel to Prevent Peri-Implant Infections in Orthopaedic Surgery: A Clinical Narrative Review D. Pressato et al. https://doi.org/10.3390/ma16155304
52. Megaprostheses for the revision of infected hip arthroplasties with severe bone loss N. Logoluso et al. https://doi.org/10.1186/s12893-022-01517-y
53. WPI Hydrogels with a Prolonged Drug-Release Profile for Antimicrobial Therapy V. Plastun et al. https://doi.org/10.3390/pharmaceutics14061199
54. Antibacterial hydrogel coating is associated with lower complication risks after complex high-risk primary and cementless hip revision arthroplasty B. Ding et al. https://doi.org/10.1302/2633-1462.66.BJO-2025-0004.R1
55. Effects of Vancomycin/Tobramycin-Doped Ceramic Composite (Polyvinyl Alcohol Composite–Vancomycin/Tobramycin–Polymeric Dicalcium Phosphate Dihydrate) in a Rat Femur Model Implanted With Contaminated Porous Titanium Cylinders F. Aboona et al. https://doi.org/10.1016/j.arth.2024.04.076
56. Local Antibiotic Delivery Systems and Their Applications in Orthopaedic Surgery A. Hoveidaei et al. https://doi.org/10.2106/JBJS.OA.25.00157
57. Antibacterial coating of implants: are we missing something? C. Romanò et al. https://doi.org/10.1302/2046-3758.85.BJR-2018-0316
58. Improving Biofilm Prevention in Implant-Based Breast Surgery J. Larson et al. https://doi.org/10.1097/SAP.0000000000004520
59. Defensive antibacterial coating in revision total hip arthroplasty: new concept and early experience M. Franceschini et al. https://doi.org/10.1177/1120700020917125
60. Detection to Disruption: A Comprehensive Review of Bacterial Biofilms and Therapeutic Advances P. Maroju et al. https://doi.org/10.3390/antibiotics15040396
61. Thickness-Dependent Wetting of a Micro-Sessile Liquid Droplet on a Compliant Elastic Thin Layer K. Bertin & J. Wu https://doi.org/10.3390/app16115327
62. One-stage exchange with antibacterial hydrogel coated implants provides similar results to two-stage revision, without the coating, for the treatment of peri-prosthetic infection N. Capuano et al. https://doi.org/10.1007/s00167-018-4896-4
63. Vitamin E Phosphate Coating Stimulates Bone Deposition in Implant-related Infections in a Rat Model A. Lovati et al. https://doi.org/10.1097/01.blo.0000534692.41467.02
64. Inherent and Composite Hydrogels as Promising Materials to Limit Antimicrobial Resistance R. Carpa et al. https://doi.org/10.3390/gels8020070
65. Use of a Bioresorbable Antibacterial Coating (DAC® Hydrogel) in One-Stage Revision of Infected Knee Arthroplasty: Long-Term Study N. Logoluso et al. https://doi.org/10.3390/antibiotics15080791
66. General Assembly, Prevention, Local Antimicrobials: Proceedings of International Consensus on Orthopedic Infections J. Baeza et al. https://doi.org/10.1016/j.arth.2018.09.056
67. Cellulose-Derived Nanographene Oxide Surface-Functionalized Three-Dimensional Scaffolds with Drug Delivery Capability N. B. Erdal et al. https://doi.org/10.1021/acs.biomac.8b01421
68. Hip and Knee Section, Prevention, Prosthesis Factors: Proceedings of International Consensus on Orthopedic Infections C. Aboltins et al. https://doi.org/10.1016/j.arth.2018.09.016
69. Coating of bone implants with silica, hyperbranched polyethyleneimine, and gentamicin prevents development of osteomyelitis in a porcine model L. Jensen et al. https://doi.org/10.1016/j.mtla.2022.101473
70. Long-term anti-inflammatory effects of injectable celecoxib nanoparticle hydrogels for Achilles tendon regeneration J. Kim et al. https://doi.org/10.1016/j.actbio.2022.03.033
71. Modern Microbiological Methods to Detect Biofilm Formation in Orthopedy and Suggestions for Antibiotic Therapy, with Particular Emphasis on Prosthetic Joint Infection (PJI) P. Mikziński et al. https://doi.org/10.3390/microorganisms12061198
72. What Is the Role of Local Antimicrobial Protection for One-Stage Revision for Peri-Prosthetic Hip Infection? C. Romanò et al. https://doi.org/10.3390/antibiotics13111060
73. Bioinspired Hydrogel Coating Based on Methacryloyl Gelatin Bioactivates Polypropylene Meshes for Abdominal Wall Repair A. Serafim et al. https://doi.org/10.3390/polym12081677
74. Hydrogels for Local Drug Delivery in Biofilm-Associated Periprosthetic Joint Infection: Current Progress and Future Directions K. Kraus et al. https://doi.org/10.3390/microorganisms14091882
75. Bacterial osteomyelitis in veterinary orthopaedics: Pathophysiology, clinical presentation and advances in treatment across multiple species F. Gieling et al. https://doi.org/10.1016/j.tvjl.2019.06.003
76. Polymer-Based Coatings with Integrated Antifouling and Bactericidal Properties for Targeted Biomedical Applications D. Mitra et al. https://doi.org/10.1021/acsapm.1c00125
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78. The Potential Innovative Use of Bacteriophages Within the DAC® Hydrogel to Treat Patients With Knee Megaprosthesis Infection Requiring “Debridement Antibiotics and Implant Retention” and Soft Tissue Coverage as Salvage Therapy T. Ferry et al. https://doi.org/10.3389/fmed.2020.00342
79. Infections associated with mesh repairs of abdominal wall hernias: Are antimicrobial biomaterials the longed-for solution? O. Guillaume et al. https://doi.org/10.1016/j.biomaterials.2018.03.017
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84. Prevention of Prosthetic Joint Infection: From Traditional Approaches towards Quality Improvement and Data Mining J. Gallo & E. Nieslanikova https://doi.org/10.3390/jcm9072190
85. Distal femur replacement for infected bone defects due to end-stage periprosthetic joint infection or trauma: a staged strategy protocol using the stemless Compress® device protected with a fast resorbable antibiotic-loaded hydrogel P. Corona et al. https://doi.org/10.1007/s00590-025-04177-9
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87. Hydrogel Coating versus Calcium Sulphate Beads as a Local Antibiotic Carrier for Debridement Procedures in Acute Periprosthetic Joint Infection: A Preliminary Study D. De Meo et al. https://doi.org/10.3390/gels9090758
88. Calcium hydroxide coating for orthopedic implants: evaluation of osseointegrative and antibacterial properties in vivo S. von Hertzberg-Boelch et al. https://doi.org/10.3389/fbioe.2025.1675881
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90. Antibiotics- and Heavy Metals-Based Titanium Alloy Surface Modifications for Local Prosthetic Joint Infections J. Esteban et al. https://doi.org/10.3390/antibiotics10101270