Journal of Bone and Joint Infection
Journal of Bone and Joint Infection
JBJI
Articles | Volume 9, issue 1
Articles | Volume 9, issue 1
https://doi.org/10.5194/jbji-9-67-2024
© Author(s) 2024. This work is distributed under
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/jbji-9-67-2024
© Author(s) 2024. This work is distributed under
the Creative Commons Attribution 4.0 License.
Articles | Volume 9, issue 1
Original full-length article
 | 
15 Feb 2024
Original full-length article |  | 15 Feb 2024

Antibiotic prophylaxis before tissue biopsy has no effect on culture results in presumed aseptic revision total hip arthroplasty

Jesse D. De Groot, Roy G. B. Brokelman, Bas L. Fransen, Tim U. Jiya, and Dean F. M. Pakvis

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Short summary
We retrospectively analyzed 490 patients who underwent aseptic revision total hip replacement (R-THA) and found no difference in culture results between antibiotic prophylaxis (AP) administered before incision or after tissue biopsy. Although not significant, infection was twice as likely when AP was given after incision. Other literature also supports the benefit of pre-incisional AP. We therefore believe AP should be given pre-incision to prevent unnecessarily exposing patients to infections.
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