Articles | Volume 9, issue 1
Original full-length article
29 Jan 2024
Original full-length article |  | 29 Jan 2024

Diagnostic cutoff values of synovial fluid biomarkers for acute postoperative prosthetic joint infection: a systematic review and meta-analysis

Marta Sabater-Martos, Marc Ferrer, Laura Morata, Alex Soriano, and Juan Carlos Martínez-Pastor

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Cited articles

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Bedair, H., Ting, N., Jacovides, C., Saxena, A., Moric, M., Parvizi, J., and della Valle, C. J.: The mark coventry award: Diagnosis of early postoperative TKA infection using synovial fluid analysis, Clin. Orthop. Relat. R., 469, 34–40,, 2011. 
Christensen, C. P., Bedair, H., Valle, C. J. D., Parvizi, J., Schurko, B., and Jacobs, C. A.: The natural progression of synovial fluidwhite blood-cell counts and the percentage of polymorphonuclear cells after primary total knee arthroplasty a multicenter study, J. Bone Joint Surg. A, 95, 2081–2087,, 2013. 
Short summary
This is a meta-analysis of six studies describing the cutoff values of white blood cell count and polymorphonuclear percentage in synovial fluid for the diagnosis of acute postoperative peri-prosthetic joint infection (PJI). 
We found that both the WBC count and PMN percentage are good markers for diagnosis of acute postoperative PJI. However, the synovial WBC count is more powerful in diagnosing acute postoperative PJI.