Journal of Bone and Joint Infection
Journal of Bone and Joint Infection
JBJI
Articles | Volume 9, issue 3
Articles | Volume 9, issue 3
https://doi.org/10.5194/jbji-9-143-2024
© Author(s) 2024. This work is distributed under
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/jbji-9-143-2024
© Author(s) 2024. This work is distributed under
the Creative Commons Attribution 4.0 License.
Articles | Volume 9, issue 3
Brief report
 | 
14 May 2024
Brief report |  | 14 May 2024

No differences in outcomes with stopping or continuing antibiotic suppression in periprosthetic joint infections

Daisuke Furukawa, Megan Dunning, Sa Shen, Amy Chang, Jenny Aronson, Derek F. Amanatullah, Gina A. Suh, and Shanthi Kappagoda

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Latest update: 01 Apr 2025
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Short summary
The role of long-term antibiotics after debridement, antibiotics, and implant retention (DAIR) for periprosthetic joint infections is unclear. Patients with eventual cessation of antibiotics had similar outcomes to those who remained on chronic antibiotic suppression (failure rate of 11 % for both groups). This study importantly highlights a potential opportunity to prevent unnecessary antibiotic use and spare patients from the risk of side effects and development of resistant organisms. 
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