Articles | Volume 9, issue 2
https://doi.org/10.5194/jbji-9-137-2024
https://doi.org/10.5194/jbji-9-137-2024
Review
 | 
30 Apr 2024
Review |  | 30 Apr 2024

Sex-related differences in periprosthetic joint infection research

Domenico De Mauro, Cesare Meschini, Giovanni Balato, Tiziana Ascione, Enrico Festa, Davide Bizzoca, Biagio Moretti, Giulio Maccauro, and Raffaele Vitiello

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Cited articles

Balato, G., Roscetto, E., Vollaro, A., Galasso, O., Gasparini, G., Ascione, T., Catania, M. R., and Mariconda, M.: Bacterial biofilm formation is variably inhibited by different formulations of antibiotic-loaded bone cement in vitro, Knee Surg. Sports Traumatol. Arthrosc. Off. J. ESSKA, 27, 1943–1952, https://doi.org/10.1007/s00167-018-5230-x, 2019a. 
Balato, G., Barbaric, K., Bićanić, G., Bini, S., Chen, J., Crnogaca, K., Kenanidis, E., Giori, N., Goel, R., Hirschmann, M., Marcacci, M., Amat Mateu, C., Nam, D., Shao, H., Shen, B., Tarabichi, M., Tarabichi, S., Tsiridis, E., and Tzavellas, A.-N.: Hip and Knee Section, Prevention, Surgical Technique: Proceedings of International Consensus on Orthopedic Infections, J. Arthroplasty, 34, S301–S307, https://doi.org/10.1016/j.arth.2018.09.015, 2019b. 
Basilico, M., Vitiello, R., Oliva, M. S., Covino, M., Greco, T., Cianni, L., Dughiero, G., Ziranu, A., Perisano, C., and Maccauro, G.: Predictable risk factors for infections in proximal femur fractures, J. Biol. Regul. Homeost. Agents, 34, 77–81, 2020. 
Bizzoca, D., Solarino, G., Pulcrano, A., Brunetti, G., Moretti, A. M., Moretti, L., Piazzolla, A., and Moretti, B.: Gender-Related Issues in the Management of Low-Back Pain: A Current Concepts Review, Clin. Pract., 13, 1360–1368, https://doi.org/10.3390/clinpract13060122, 2023. 
Bouji, N., Wen, S., and Dietz, M. J.: Intravenous antibiotic duration in the treatment of prosthetic joint infection: systematic review and meta-analysis, J. Bone Joint Infect., 7, 191–202, https://doi.org/10.5194/jbji-7-191-2022, 2022. 
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Short summary
This study investigates sex-related differences in periprosthetic Joint Infections (PJIs) after total joint arthroplasty. A systematic review of nine studies reveals a higher risk of infectious complications in males compared to females, as indicated by statistically significant findings in half of the studies. This underscores the need for ongoing sex-related analysis to enhance evidence and insights in the field of PJIs.
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