Articles | Volume 7, issue 2
https://doi.org/10.5194/jbji-7-61-2022
https://doi.org/10.5194/jbji-7-61-2022
Review
 | 
25 Mar 2022
Review |  | 25 Mar 2022

Short and oral antimicrobial therapy for diabetic foot infection: a narrative review of current knowledge

Steven M. Maurer, Zehra S. Hepp, Shawna McCallin, Felix W. A. Waibel, Federico C. Romero, Yılmaz Zorman, Benjamin A. Lipsky, and İlker Uçkay

Cited articles

Abbas, M., Uçkay, I., and Lipsky, B. A.: In diabetic foot infections antibiotics are to treat infection, not to heal wounds, Expert. Opin. Pharmacother., 16, 821–832, https://doi.org/10.1517/14656566.2015.1021780, 2015. 
Agostinho, A., Renzi, G., Haustein, T., Jourdan, G., Bonfillon, C., Rougemont, M., Hoffmeyer, P., Harbarth, S., and Uçkay, I.: Epidemiology and acquisition of extended-spectrum beta-lactamaseproducing Enterobacteriaceae in a septic orthopedic ward, Springerplus, 2, 91, https://doi.org/10.1186/2193-1801-2-91, 2013. 
Al-Mayahi, M., Cian, A., Kressmann, B., de Kalbermatten, B., Rohner, P., Egloff, M., Jafaar, J., Malacarne, S., Miozzari, H. H., and Uçkay, I.: Associations of diabetes mellitus with orthopaedic infections, Infect. Dis. (Lond.), 48, 70–73, https://doi.org/10.3109/23744235.2015.1082620, 2016. 
Aragón-Sánchez, J., Víquez-Molina, G., and López-Valverde, M. E.: Controversial Issues Regarding Positive Bone Margins in Surgery for Diabetic Foot Osteomyelitis: A Pilot Study, Int. J. Low Extrem. Wounds, 15347346211041267, https://doi.org/10.1177/15347346211041267, 2021. 
Atway, S., Nerone, V. S., Springer, K. D., and Woodruff, D. M.: Rate of residual osteomyelitis after partial foot amputation in diabetic patients: a standardized method for evaluating bone margins with intraoperative culture, J. Foot Ankle Surg., 51, 749–752, https://doi.org/10.1053/j.jfas.2012.06.017, 2012. 
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Short summary
The treatment of diabetic foot osteomyelitis requires a multidisciplinary approach. The optimal duration of systemic antibiotic therapy after surgical debridement or amputation is currently unknown. In recent years, emerging research on this clinical topic has been carried out. Therefore, we review the current knowledge and recommendations regarding the duration of antibiotic therapy for diabetic foot osteomyelitis.