Articles | Volume 7, issue 6
https://doi.org/10.5194/jbji-7-221-2022
https://doi.org/10.5194/jbji-7-221-2022
Original full-length article
 | 
10 Nov 2022
Original full-length article |  | 10 Nov 2022

A desirability of outcome ranking (DOOR) for periprosthetic joint infection – a Delphi analysis

Brenton P. Johns, David C. Dewar, Mark R. Loewenthal, Laurens A. Manning, Amit Atrey, Nipun Atri, David G. Campbell, Michael Dunbar, Christopher Kandel, Amir Khoshbin, Christopher W. Jones, Jaime Lora-Tamayo, Catherine McDougall, Dirk Jan F. Moojen, Jonathan Mulford, David L. Paterson, Trisha Peel, Michael Solomon, Simon W. Young, and Joshua S. Davis

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Cited articles

Atrey, A., Khoshbin, A., Rolfson, O., Campbell, D., Wood, G., Bohm, E., Jones, C., Kandel, C., Davis, J., Atri, N., Abdelbary, H., Moojen, D. J., Dunbar, M., Manning, L., Paxton, E. W., Yates, P., Waddell, J. P., Ravi, B., and Reed, M.: Infection: The Final Frontier of Arthroplasty Management: A Proposal for a Global Periprosthetic Joint Infection Registry from a Multinational Collaborative Group, the GAIA (Global Arthroplasty Infection Association), J. Bone Joint Surg. Am., 103, e22, https://doi.org/10.2106/jbjs.20.01517, 2021. 
Barry, J. J., Geary, M. B., Riesgo, A. M., Odum, S. M., Fehring, T. K., and Springer, B. D.: Irrigation and Debridement with Chronic Antibiotic Suppression Is as Effective as 2-Stage Exchange in Revision Total Knee Arthroplasty with Extensive Instrumentation, J. Bone Joint Surg. Am., 103, 53–63, https://doi.org/10.2106/jbjs.20.00240, 2021. 
Celestin, A. R., Odom, S. R., Angelidou, K., Evans, S. R., Coimbra, R., Guidry, C. A., Cuschieri, J., Banton, K. L., O'Neill, P. J., Askari, R., Namias, N., Duane, T. M., Claridge, J. A., Dellinger, E. P., Sawyer, R. A., and Cook, C. H.: Novel Method Suggests Global Superiority of Short-Duration Antibiotics for Intra-abdominal Infections, Clin. Infect. Dis., 65, 1577–1579, https://doi.org/10.1093/cid/cix569, 2017. 
Cobo, J., Miguel, L. G., Euba, G., Rodríguez, D., García-Lechuz, J. M., Riera, M., Falgueras, L., Palomino, J., Benito, N., del Toro, M. D., Pigrau, C., and Ariza, J.: Early prosthetic joint infection: outcomes with debridement and implant retention followed by antibiotic therapy, Clin. Microbiol. Infect., 17, 1632–1637, https://doi.org/10.1111/j.1469-0691.2010.03333.x, 2011. 
Conner-Spady, B. L., Marshall, D. A., Bohm, E., Dunbar, M. J., and Noseworthy, T. W.: Comparing the validity and responsiveness of the EQ-5D-5L to the Oxford hip and knee scores and SF-12 in osteoarthritis patients 1 year following total joint replacement, Qual. Life Res., 27, 1311–1322, https://doi.org/10.1007/s11136-018-1808-5, 2018. 
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Short summary
Treatments for prosthetic joint infections (PJIs) are often assessed using a success or failure endpoint. Yet, this can fail to capture important outcomes for patients. A desirability of outcome ranking (DOOR) is a way of evaluating treatments in a more patient-focused form. This study found an outcome ranking using joint function, infection cure and quality of life. This helps to answer what are we trying to achieve for patients with PJI and how we measure the effectiveness of PJI treatments.